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Safety information about using Tacrolimus Tacrolimus,109581-93-3,guidechem Tacrolimus, which is also known as FK-506 monohydrate, Product Number Brand is F4679. It a kind of white or off-white crystalline powder. The Molecular Formula is C44H69NO12, Molecular Weight is 804.01816, and the CAS NO. is 104987-11-3. It is an immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system and so lower the risk of organ rejection. It is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, and the skin condition vitiligo. It is a 23-membered macrolide lactone discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. It reduces interleukin-2 (IL-2) production by T-cells. Tacrolimus is used for the short-term relief of eczema flare-ups, and as intermittent treatment in the long-term management of eczema. It is used when topical corticosteroids have not been effective, or when they should not be used, for example in people who have experienced unacceptable side effects related to topical steroids. So ,I will give you some important safety information about using Tacrolimus: 1.Avoid or limit exposure to the sun while you are using tacrolimus ointment, even when it is not on your skin. Avoid using sunlamps or tanning booths during treatment with it. Wear protective clothing if you must be outside for more than a short time. Discuss with your doctor what other types of protection from the sun you should use. 2.Tacrolimus ointment should be used for short periods of time. If recommended by your doctor, treatment may be repeated with breaks in between. Do not use it continuously for a long time unless directed by your doctor. 3.You can use a skin moisturizer while you use tacrolimus ointment as directed by your doctor. Talk with your doctor before you use any other medicines or cleansers on your skin. If you use a moisturizer, apply it after you apply this medicine. 4.Drinking alcohol while you are using tacrolimus ointment may cause your skin or face to become flushed or red and feel hot. Discuss any questions or concerns with your doctor. If you develop a skin infection, your symptoms get worse, or your symptoms do not improve after 6 weeks of treatment, contact your doctor. 5.Tacrolimus ointment may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.


6.Tell your doctor or dentist that you take tacrolimus ointment before you receive any medical or dental care, emergency care, or surgery. 7.Tacrolimus ointment should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed. 8.PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using tacrolimus ointment while you are pregnant. This chemical is found in breast milk. Do not breast-feed while taking it. Frankie is the freelance writer for e-commerce website in the chemistry. Guidechem.com is just a place for you to look for some chemicals.

Safety information aboutu sing Tacrolimus  

It is a23-memberedmacrolidelactone discoveredin 1984from the fermentation brothofa Japanese soil sample that contained the bacteria Streptom...

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