Accurate plant genome editing technologies have opened up new avenues for crop improvement and the development of more sustainable agricultural systems. CRISPR platforms derived from prokaryotes, in particular, enable precise manipulation of the crop genome, enabling the development of high-yielding and stress-tolerant crop varieties. Nanotechnology has the potential to further accelerate the development of a novel molecular toolbox by introducing the possibility of a rapid, universal delivery method for species-independent genome editing.