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Box 28 Lewisville, Texas 75057 800.227.0627 (Toll Free) www.biosyn.com

Coupling of additional modifications

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x

x

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x

Gene silencing

Immobilisation on solid surfaces

Biological functionalisation assays

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Structure-relationship assays

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Antisence assays

Gene synthesis

x

Microarrays

Mutagenesis

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Hybridisation

Cloning / Ligation

Fragment Analysis

Sequencing

FRET

Real-time PCR

PCR

Applications

Enhanced purification PAGE Functional Groups NH2 (Aminolink) SH (Thiollink) PO4 (Phosphate)

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x

Biotin

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DIG (Digoxigenin)

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x

x

x

HRP (Horseradish Peroxidase) Fluorescence Dyes Fluorescent dyes

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x

x

x

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x

x

x

Double-labelled fluorescent probes Dye-dT

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Dabcyl

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x

x

x

x

x

x

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x

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Internal Modifications PTO (Phosphothioate-Oligo)

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x

Methyl-Phosphonate-Oligo

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x

2´ O-Methyl-RNA

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x

2´deoxy Inosine

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x

x

2´deoxy Uridin

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x

Biotin-dT

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x

x

Amino-dT

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x

Dye-dT

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x

X x

x

dSpacer

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halogenated bases (5-BrdC, 5´Br-dU, 5-I-dC, 5-IdU) Special Modifications

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x x

Carbon Chain Spacers

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x

Ethylenglycol Spacer

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x

3´Block (C3-Spacer) Inverted End (3´-3-linkage)

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x

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x

x x

Asymmetric doubler

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x

Symmetric doubler

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x

x

x

RNA RNA si-RNA

x x



Biosynthesis Ehanced purification Applications