FERTILITY TREATMENTS INFORMATION BROCHURE
Our centre is part of UZ Brussel, the university hospital of the VUB (Free University of Brussels). The CRG is specialised in reproductive or fertility medicine. We have an international reputation as pioneers in the development of reproductive techniques and their application. Since the CRG’s creation in 1983, more than 20,000 babies have been born following fertility treatment of the parents. In addition - from our university function in the network of UZ Brussel and the VUB - the CRG acts as a training institute and engine for scientific research.
OUR MISSION Every day we want to dedicate ourselves 100% to fulfil our threefold mission on a high quality level: 100% dedication to protect and optimise the fertility of all our patients and thus help them to have a healthy child; 100% dedication for independent and innovative studies about all aspects of human fertility. For this we invest in a global exchange of researchers in our field of expertise; 100% ambition to increase the knowledge of all stakeholders – researchers, students, parents, children, etc. – as much as possible, by spreading our knowledge through education, training and communication.
FERTILITY CLINIC WITH GREAT CARE FOR PATIENTS The CRG offers its patients a broad care programme, ranging from assisted fertilisation to treatment of related reproductive problems: Hormone treatments and coitus timing Artificial insemination IVF and IVF-ICSI TESE and other operations for sperm extraction - for men with strongly reduced fertility IVM (in-vitromaturation), i.e. harvesting of unripe eggs, maturation and fertilisation in the laboratory IVF-ICSI care programme for prospective parents with a viral infection (HIV, hepatitis C) IVF-ICSI care programme for couples with a hereditary defect (PGD, PGS) Reversal of sterilisation (men and women) Miscarriage clinic - care programme for recurrent miscarriages Fertility treatments with donor material (donor sperm, donor eggs) Safeguarding the fertility of patients with a cancer diagnosis
Our medical practice is based on an accredited quality assurance system. Our care programmes are always the result of follow-up studies of patients.
(New) fertility programmes always are checked against their results in terms of: effects on patients, success rate, progress of the pregnancy, health of mother and baby.
CHANCES OF SUCCESS AT THE CRG The chart shown here is based on the results of all CRG patients who started their first IVF/ICSI treatment in 2011, without any selection (read ‘exemption’) based on their medical profile. For a number of age categories, the chart shows: The expected cumulative chances (i.e. across various attempts), of a delivery (i.e. not pregnancy or progressing pregnancy), after every started cycle, the egg retrieval which yielded at least one egg, and/or after the possible transfer of fresh embryos and possible frozen-thawed embryos – and with strict application of the legal standards regarding the number of embryos that can be transferred. On the vertical line you can see how many women (out of a hundred) in which age category will have delivered a baby after IVF-ICSI-treatment with possible transfer of fresh and frozen-thawed embryos. The horizontal line shows the number of treatment cycles.
Number of expected births Number of expected births (out of 100 woman)
100 90 80 70
_ < 36 years
_ > 43 years
36-43 years (average)
20 10 0
Number of art cycles (IVF-ICSI-FRET)
Practice has shown that it is difficult to predict your individual chances of success with an ART treatment. During the intake-consultation the CRG doctor will always try to make the most accurate assessment possible. This is based on our medical experience, but also on results of the past.
THE EFFECT OF AGE IS OBVIOUS At a young age you easily become pregnant: the first treatment cycles result in a high chance of pregnancy; At a later age every treatment cycle results in a comparable but lower cumulative chance of pregnancy - it is more difficult to get pregnant (lower chance of implantation) - it is more difficult to stay pregnant (higher risk of miscarriage); For the group of women in the 40 to 42 age category, ten out of a hundred who start the first treatment cycle will deliver a baby. After the fourth treatment cycle, 38 women out of a hundred will have delivered a baby
LEGAL RESTRICTION Belgian law lays down an absolute age limit for fertility treatment: Egg retrieval is possible up to your 45th birthday (to the day before you turn 45), For an embryo transfer the age limit is 47 (the day before you turn 48), In other words, you are required to have had your egg retrieval before your 45th birthday to qualify for an embryo transfer later. (possibly with thawed embryos)
As soon as you turn 48, you can no longer be treated in Belgium.
MEDICAL RECORD Both men and women play a key role in an ART treatment. That is why the first thing we want is a copy of you and your partnerâ&#x20AC;&#x2122;s medical records. Based on this we can see which data is missing and whether other tests are necessary before we can start the treatment. Depending on how far you live from Brussels, the gynecologist may decide that a preliminary consultation at the CRG is recommended. But if the distance is too great, the examinations and tests can also be performed in your country. You simply need to make sure the results get to us as soon as possible.
WHEN CAN THE TREATMENT BEGIN? It usually takes some time between your initial contact with the centre and the official start of your treatment. The exact starting date depends on your options and wishes as well as our planning. If an initial consultation is necessary, this will generally be planned about six weeks before the start of your treatment. The various tests and examinations (talk with the gynaecologist and the CRG counsellor, ultrasound scans, sperm analysis, etc.) which will have to be performed on both you and your partner take about a day and a half to complete. You will be notified of the precise duration of the examinations and the date you are expected in Brussels in advance Once we have all the results of the preliminary tests, a treatment schedule will be proposed to you.
WHEN WILL YOU NEED TO BE IN BRUSSELS? The precise dates when you need to be in Brussels depend on a number of factors:
the medical advice of the gynaecologist at the CRG, whether or not you had an initial consultation at the centre. If you didnâ&#x20AC;&#x2122;t, you will be asked to come on day seven of your ovarian stimulation; your personal circumstances and desires, when it is possible for both of you to travel to Brussels, and how long you can stay; the medical facilities in your own country.
In short, some couples come to Brussels from the start of the stimulation phase, some during the stimulation and others only right at the end. The precise date when you are expected at the CRG is determined for every couple individually. There are no hard and fast rules. Our only aim is that the treatment proceeds as effectively and comfortably as possible.
United Kingdom London (372km)
the Netherlands Amsterdam (210km)
BRUSSELS Germany Berlin (763km)
France Paris (313km) Luxembourg (236km)
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