Issuu on Google+

Stanford Chemicals

Researches on Weight Loss via Herbal Medicines in China In the past, individual herbal medicines for weight loss reported in China included lotus leaf, coix seed, phaseolus calcaratus, Polygonum cuspidatum, Rhizoma atractylodis, Rhizoma alismatis, Capillary artemisia, Folium sennae, onion, Radix bupleuri, bulrush root, honeysuckle, Radix salviae miltiorrhizae, Paeonia lactiflora, leonurus, pseudo-ginseng, raw hawthorn, trogopterus dung, Rhizoma cyperi, Rhizoma sparganii, curcuma zedoary, Caulis spatholobi, Angelica sinensis, Ligusticum wallichii, Eclipta alba, Ligustrum lucidum Ait, fleece-flower root, radix rehmanniae, Cornus officinalis and chrysanthemum.

An experiment was conducted to feed mice with high-fat fodder containing eustoma-water extracts, and the result showed that weight and fat mass around uterus of mice were obviously reduced on comparing groups of high-fat fodder containing 5% eustoma-water extracts with control groups. Meanwhile, TG level in liver was somewhat reduced. Total platycodin was thought to inhibit the activity of pancreatic lipase by 41.7%, platycodin D, platycodin A, and platycodin C of which separately inhibited the activity at level of 34.8%, 3.3% and 5.2% for purpose of weight loss through inhibiting absorption of dietary fat.

When Fallopia multiflora extract was fed to rats via oral administration, the result showed food intake and weight of rats were obviously reduced. The activity of liver FAS of rats in treatment groups was lower than that in control groups (double distilled water in control groups). Wang et al. established a diet-induced obesity model of rats by feeding dietary fodder and observed action of Yuncaoning on rats with diet-induced obesity. Recording weight, body length, tail length, Leeâ&#x20AC;&#x2122;s index, fat mass around reproductive organs and number of adipose cells, after the administration, indexes above were all obviously improved (P<0.05). It was confirmed that Yuncaoning has a preventively anti-obesity action on rats with diet-induced obesity.

Garlic crude extracts was found to obviously reduce level of blood lipid of rats with hyperlipidemia. Meanwhile, it also reduced body weight, liver weight and fat wet weight in

Stanford Chemicals

body of rats. Further researches confirmed that allicin in garlic is diallyltrisulfide, which is stable and has actions like lowering cholesterol. Randomly assigning SD rats that were established to a high-lipid model to three dose groups (low, middle and high) and one control group and feeding high fat-diet treated rats for 30 days following by executing and weighing body weight and fat wet weight in body and at last, calculating body fat. The result showed that body weight, weight gain and fat wet weight in body of rats in low, middle and high dose treatment groups were obviously reduced compared with the control group, and body fat of rats in low and middle dose groups were also obviously reduced compared with the control group (P<0.05).

Ning et al. conducted an intragastric administration with ganoderma lucidum mycelia fermentation extracts to mice with diet-induced obesity and infused NS to control groups, and observed changes of body weight. The result showed that ganoderma lucidum mycelia fermentation extracts obviously reduced the body weight of mice with diet-induced obesity.

Another intragastric administration was carried out with Kudingcha decoction to rats with obesity for 4 weeks, and they found that Kudingcha obviously reduced total serum cholesterol and TG, and liver weight and fat wet weight were also reduced. Huang Linfang established a diet-induced obesity model of mice by feeding them with dietary fodder and administrated with water decoction of Kudingcha produced in Sichuan via intragastric administration, and then set up several groups, measured and calculated each index of mice in each treatment group like body weight and fat wet weight. Anti-obesity action of Kudingcha was observed on mice with diet-induced obesity and found the effect was obvious (P<0.01).

About Stanford Chemicals

Stanford Chemicals is a worldwide supplier of phytochemicals, pharmaceutical intermediates, catalysts, lab equipment and a variety of special fine chemical products since 1994. To meet increasing demands for herbal extracts in nutraceutical, pharmaceutical and cosmetic industries, Stanford Chemicals is established and now carries hundreds kinds of herbal extracts, including botanical ingredients and standard herbal extracts

Researches on weight loss via herbal medicines in china