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The Pharmacologist is published and distributed by the American Society for Pharmacology and Experimental Therapeutics.

Contents 1 Introduction and River Blindness: The Chip Shot 2 Ivermectin Heard Around the World 15 Taxol: Barking Up the Right Tree and the Dawn of 27 Chlorpromazine Antipsychotics 40 Cortisone: A Miracle with Flaws 52 Typhus: War and Deception in 1940’s Poland Promise and Perils of Pharmacy 61 The Compounding Barriers: The Life and Work of 74 Breaking Rosalyn Yalow

86 Enbrel: A biotechnology breakthrough

THE PHARMACOLOGIST PRODUCTION TEAM Rich Dodenhoff Catherine L. Fry, PhD Dana Kauffman Judith A. Siuciak, PhD Suzie Thompson COUNCIL President John D. Schuetz, PhD President-Elect Edward T. Morgan, PhD Past President David R. Sibley, PhD Secretary/Treasurer John J. Tesmer, PhD Secretary/Treasurer-Elect Margaret E. Gnegy, PhD Past Secretary/Treasurer Charles P. France, PhD Councilors Wayne L. Backes, PhD Carol L. Beck, PharmD, PhD Alan V. Smrcka, PhD Chair, Board of Publications Trustees Mary E. Vore, PhD Chair, Program Committee Michael W. Wood, PhD FASEB Board Representative Brian M. Cox, PhD Executive Officer Judith A. Siuciak, PhD The Pharmacologist (ISSN 0031-7004) is published quarterly in March, June, September, and December by the American Society for Pharmacology and Experimental Therapeutics, 9650 Rockville Pike, Suite E220, Bethesda, MD 20814-3995. Copyright © 2018 by the American Society for Pharmacology and Experimental Therapeutics, Inc. All rights reserved. If you would like a print subscription to The Pharmacologist, please contact the membership department at membership@aspet.org. ASPET assumes no responsibility for the statements and opinions advanced by contributors to The Pharmacologist.

The Pharmacologist • Special Edition

Profile for ASPET

2018 Special Compilation Issue of The Pharmacologist  

ASPET is pleased to present the second in a series of special editions of our quarterly news magazine, The Pharmacologist. This special com...

2018 Special Compilation Issue of The Pharmacologist  

ASPET is pleased to present the second in a series of special editions of our quarterly news magazine, The Pharmacologist. This special com...