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President’s Message Dear Colleagues, The tragic death of Professor Anthony Marmarou, the President of the 5th Hydrocephalus Workshop, has left a great gap not only in the planning of this meeting but also in the basic science and clinical research in Hydrocephalus. His final message to us was that we should “continue”. It was extremely important to Tony that we continue to work to better the lives of those with hydrocephalus. Specifically he has asked me to lead the meeting in Crete in May of this year. I am committed to continuing his important work and ask for the support of all of you to make this a successful Workshop. Under the leadership of Professor Marmarou and Workshop Vice President Dr. Kouzelis, most of the planning for the meeting as well as the choice of invited speakers has already been done. The venue for the meeting at the Creta Maris Convention & Golf Resort on the beautiful and historically critical island of Crete is perfect for the sharing of information and solving of critical controversies in an enjoyable setting. Your ideas matter and we are looking forward to hearing what you have to say. I extended the deadline for the submission of abstracts until March 15 but will still commit to having the abstracts reviewed and the notifications complete by April 1. The deadline for early registration will also be extended until March 15. Best Regards,

Harold L. Rekate M.D. President of the 5th International Hydrocephalus Workshop

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Vice-President’s Address Dear Colleagues and Friends, The Hellenic Neurosurgical Society is particularly pleased to be involved once again this year in organizing the 5th International Hydrocephalus Workshop on the charming Aegean island of Crete. Drawing on the fact that the previous workshops were a complete success, we believe that this event will be a major turning point, and will make a significant contribution to the effort to ensure further understanding of timely diagnosis and treatment of hydrocephalus. The wide number of topics covered, the outstanding credentials of our guest speakers and the option of all workshop participants to become actively involved in its proceedings, guarantee that this objective will be achieved. We would like to hope that we will be able to follow Ariadne’s lost thread through the ruins of the ancient Minoan labyrinth on the mythical island of Crete, and find the much sought after solution to the ancient Hippocratic riddle of hydrocephalus. We are also very pleased that this International Hydrocephalus Workshop will follow the 24th Annual Hellenic Congress of Neurosurgery with international participation and the 4th Annual Neurosurgery Nurses Meeting (19 - 20 May 2010). Simultaneous interpretation of the proceedings into English and the presentation of papers in both Greek and English will also allow you to participate in our Society’s Congress which you are most welcome to attend. The members of the Organizing Committee are making every effort to ensure that you have an unforgettable stay and hope that the island’s boundless natural beauty, Crete’s famed diet and entertainment, as well as the warm local welcome will make sure that the 5th International Hydrocephalus Workshop will become one of your sweetest memories. Best Regards,

Konstantinos Kouzelis Vice President of the 5th International Hydrocephalus Workshop

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Organizing & Scientific Committee President

Harold L. Rekate

Vice President

Konstantinos Kouzelis

Gen. Secretary

Panagiotis Selviaridis

Members

Alexandros Andreou Georgios Arhontakis Dimitris Arvanitakis Manolis Chatzidakis Nikolaos Foroglou Konstantinos Fountas Evangelos Markakis Ioannis Mpaltas Georgios Orfanidis Konstantinos Paterakis Ioannis Patsalas Antonis Vakis Vasilis Varsos

Invited Speakers Gunes Aygok, M.D. Ph.D. Marek Czosnyka, Ph.D. Harold F Young, M.D. Neil Graff-Radford, M.D. Andre Grotenhuis, M.D. Masatsune Ishikawa, M.D. Ph.D. John Kestle, M.D. Petra Klinge, M.D. Ph.D. Mark Luciano, M.D. Ph.D. Michael Pollay, M.D. Ph.D. Norman Relkin, M.D. Ph.D Carsten Wikkelso, M.D. Ph.D. Michael Williams, M.D.

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Crete

will host the 5th International Hydrocephalus Workshop Crete is the southest point of Europe in the crossroad of three continents and five seas. It is the meeting point of different populations, by ancient and disparate cultures of centuries. It is the largest island in Greece and the fifth largest in the Mediterranean Sea, with a unique blend of elements from the creative assimilation of various cultural forms in a natural frame of astonishing beauty. Crete is full of beautiful beaches, traditional villages, each with its own history and huge variety of gorgeous landscapes. Crete’s history dates back to 5,000 years ago. Crete was the centre of the oldest Greek civilization, the Minoan civilization (circa 2600 - 1454 BC), which was destroyed by natural disaster. As a Greek city state, Crete successively became part of the Roman Empire, the Byzantine Empire, the Venetian Republic, the Ottoman Empire and the modern state of Greece. The unique combination of tradition with its modern life and the amazing scenery makes Crete one of the world’s favourite travel destinations.

Venue & Accommodation The Hellenic Neurosurgical Society and the Department of Neurosurgery of the Medical College of Virginia (Commonwealth University, USA) in affiliation with the International Society for Hydrocephalus and CSF Disorders have the pleasure to invite you to Crete from 20-23 May 2010 for the 5th International Hydrocephalus Workshop, which will take place at Creta Maris Convention & Golf Resort in Hersonissos.

Creta Maris Convention & Golf Resort Limin - Hersonissos, 70014, Crete, Greece T: +30 28970 27000 F: +30 28970 22130 W: www.maris.gr

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Situated 24 km east of the Heraklion International Airport “N. Kazantzakis”, it is close to the fishing village of Hersonissos, a long sweeping bay of sandy beach and crystal clear water. The conference centre directly connected to the hotel, covers an area of 6.000m² and can accommodate up to 5.000 delegates in its 68 halls. The traditional Cretan hospitality is combined with high quality accommodation.

Hotel Booking Please duly complete and send the Registration Form to ARTION Conferences & Events in order to make a reservation in the suggested hotel.

Prices per room/day • • • • •

Single room Double room Triple room Suite for single use Suite for max 2 persons

155 € 175 € 235 € 250 € 280 €

Hotel prices include breakfast and all taxes. Extra services such as the mini bar, telephone calls, internet, etc. are provided at an additional charge. Prices are per room per day (minimum stay 3 nights).

Thematic Sessions Progress and Controversies in Treatment of Adult and Pediatric Hydrocephalus Advances in Management of Hydrocephalus Pathophysiology Experimental Studies Less Invasive Studies in INPH Identifying Shunt Responders Outcome Scales Clinical Experience in ETV Mathematical Modeling Pulsatile Wave from Utility CSF Outflow Resistance Utility Shunt Technology CSF Biomarkers

MRI in Hydrocephalus Adjustable vs Fixed Valves Anti-Siphon Devices ICP in Hydrocephalus Tap vs ELD Utility Influence of Co-Morbidity Alzheimer and NPH Parkinson’s and NPH Guidelines Clinical Trials CSF and Interstitial Fluid

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Preliminary Programme Thursday, 20 May 20:00

Official Opening Ceremony – Welcome Reception 5th International Hydrocephalus Workshop

Friday, 21 May Scientific Session 1 08:00 – 10:00 Lectures Discussion 10:00 – 10:30 Coffee with Exhibitors 10:30 – 12:00 Oral Presentations 12:00 – 13:00 Poster Presentations 13:00 – 14:00 Lunch and Poster Viewing Scientific Session 2 14:00 – 15:00 Special Session Honoring Anthony Marmarou 15:00 – 15:30 Oral Presentations 15:30 – 16:00 Coffee Break 16:00 – 16:30 Oral Presentations 16:30 – 17:30 Poster Presentations

Saturday, 22 May Scientific Session 3 08:30 – 10:30 Oral Presentations 10:30 – 11:00 Coffee Break 11:00 – 13:00 Special Session Lectures Discussion 13:00 – 14:00 Lunch and Poster Viewing

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Scientific Session 4 14:00 – 15:00 Lectures Discussion 15:00 – 15:30 Coffee Break 15:30 – 16:00 Oral Presentations 16:00 – 17:30 Poster Presentations 20:30 Gala Dinner

Sunday, 23 May Scientific Session 5 09:00 – 10:30 Oral Presentations 10:30 – 11:00 Coffee with Exhibitors 11:00 – 12:30 Oral Presentations 12:30 – 13:30 Lectures Discussion 13:30 – 14:00 Closing Remarks

Call For Papers The Scientific Committee welcomes the submission of original contributions on the progress and controversies in hydrocephalus. Accepted papers will be presented as oral or poster presentations. Only a rather limited number of the most important contributions will be selected for oral presentations, as there will be only plenary, and no parallel, sessions.

Submission of Abstracts Abstracts must be submitted not later than March 15, 2010 by one of the following methods: 1. sending email to the address: hydrocephalus10@artion.com.gr 2. filling in the on line submission form www.hydrocephaluscrete2010.gr Abstracts sent by post or fax will not be accepted. Should you need any help or advice you may address to the Workshop Secretariat email address: hydrocephalus10@artion.com.gr Abstracts will be reviewed by the Scientific Committee only if accompanied by the remittance of the registration fees of at least the principal/presenting author. If your abstract is not accepted, the registration fees will be reimbursed, if a written request is received within 20 days, following your notification on the outcome of your abstract’s review. After that date the general cancellation policy will apply. 7


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Abstract Contents Abstracts must be written in English in MS Word format and must include: •Title (in capital letters) •Authors Family name should follow the initial of the first name and then follows the subscript. The name of presenting author should be underlined and author names should be separated by comma. •Institution The name of Institution should be written in small letters. When more than one institution is mentioned, then the correspondence between authors and institutions should be done with numbers and not symbols. •Text Maximum length 250 words to include: Introduction/ Objectives Materials and Methods Results Discussion/ Conclusions •Address, fax and email of the principal author for correspondence

Audiovisual Equipment Facilities for laptop use, power point presentation and Computer Assisted Presentation will be available.

Posters Posters will be displayed in a special room next to the main amphitheatre.

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Certification - Award of Points Certificates of Attendance will be issued at the end of the Workshop and will be given to the participants who will attend the Workshop. Attending the 5th International Hydrocephalus Workshop is endorsed by Continuing Medical Education (C.M.E.) points.

Registration Procedure How to Register Registration to the 5th International Hydrocephalus Workshop is made either by duly completing and sending to ARTION Conferences & Events the Registration Form or by filling in the on line Registration Form (www.hydrocephaluscrete2010.gr). For early registration fee the form should reach the Workshop Secretariat before 15 March 2010. All participants will receive confirmation of their registration. Please complete a separate form per participant (only one accompanying person can be included on the same form) and return it no later than 1 May 2010 by fax or email to the Workshop Secretariat ARTION Conferences & Events.

Registration Fees

Until 15/3/2010 From 16/3/2010 Full Participant 450 € 500 € Resident 300 € 350 € Accompanying Person 300 € 300 € Free attendance at the 24th Annual Hellenic Congress of Neurosurgery (obligatory registration at Workshop) The registration fee includes the attendance at the Workshop, Workshop material, entrance to the poster sessions and exhibition area as well as coffee breaks, lunches and dinners according to the course programme. Registration fees also cover participation to the 24th Annual Hellenic Congress of Neurosurgery, for those wishing to attend. The accompanying person’s fee includes two tours of the cultural programme of your choice and participation to all social and cultural events.

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Commercial Exhibition - Sponsorships During the 5th International Hydrocephalus Workshop an exhibition of technical equipment and pharmaceutical products will take place in a spacious area adjacent to the Workshop room. The Workshop is also open for sponsors who would like to be advertised through the Communication Programme. Those interested in participating are kindly requested to contact the Workshop Secretariat as early as possible.

Useful Information Important Dates

Abstract submission deadline Early bird registration deadline Abstract acceptance notification

March 15, 2010 March 15, 2010 April 1, 2010

Social Events

Opening Ceremony - Welcome Reception May 20, 2010 Gala Dinner May 22, 2010

20:00 20:30

Official Language of the Workshop

The official language of the Workshop will be English and Greek.

Interpretation

Interpretation will be available during the Workshop from and to English & Greek.

Internet Facilities

WI-FI connection is provided as well as a business centre for e-mail access.

Heraklion International Airport “N. Kazantzakis”

The Airport is a short, 5 km drive from the city centre of Heraklion.

Time

Greece is 2 hours ahead of Greenwich Mean Time (GMT +2) throughout the year.

Language

Greek is the official language while English is widely spoken.

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Currency

The Greek currency is EURO. Credit cards are widely used in most establishments. Most currencies and traveller’s cheques can easily be changed either at banks, hotels or money-changers with some handling charges.

Weather in May

The weather in Crete becomes warm and sunny. Rain is unlikely to occur past May 10. In May it is the peak of blooming and vegetation with temperatures ranging between 17°C to 25°C. The «meltemi» seasonal North winds have not yet started to blow, the sea is calm and nature is at its best. May is considered the best month for outdoor activities. A jacket will prove useful for the night.

Power Supply

The standard current in Greece is 220 volts. Plugs are European standard with two round pins.

Useful Phones

Police* Tourist police station Ambulance* Fire* Emergency phone** Phone book information* 11888

100 +30 2310 554870, +30 2310 554871 166 199 112

*It refers to a local number and can be used only from a local phone. **It refers to a European number. After a recorded message in English and Greek, an operator receives the call in English, French or Greek, puts the caller through to the necessary service, and assists with interpretation, if necessary. For any further information please contact the 5th International Hydrocephalus Workshop Secretariat, ARTION Conferences & Events.

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Cultural Programme & Visits Rethymno - Chania 21.05.2010 Friday

Minimum Participation 20 persons

You start early in the morning at the panoramic coastal highway that’s heading towards the west of Crete and Chania. Chania, Crete’s most beautiful town, built on the sea, represents a satisfactory mixture of old and new traditions both in architechure and in the way of life. The old town, with its beautiful port, consists of buildings from both the Venetian and Turkish periods. Walking through the narrow streets is like a trip through the history of Crete. Here, around the crescent shaped harbor, you will also find many excellent restaurants, bars and small shops, as well as the famous cruciform covered market, with its middleeastern atmosphere. The unique melting pot of history, which forms this town, is part of its enduring charm. On your way back, the journey continues to Rethymno, a noteworthly town full of contrasts, distinguished by its history and the relics of former oppressors. The town nestles against the edge of the sea. It lies approximately half-way between Heraklion and Chania.

Time Schedule 08:30-19:00 Price 73 € per person Includes bus transfer, English guide & lunch

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Phaestos - Gortyna - Matala 22.05.2010 Saturday

Minimum Participation 20 persons

Bus-ride through the fertile Plains of Messara with stops at the great archaeological sites of Gortyna and plenty of time for swimming at Matala. You will pass vineyards - the center of the sultana producing industry on the island and others, where grapes are cultivated for the Malvasia wine - which flank the eastern ridges of the Ida Mountain range. And then descend the foothills of the Ida Mountains and come to the Messara valley, Crete’s largest and most fertile area of agricultural production. You will first visit Phaestos, the second largest Minoan palace, where King Radamanthos, brother of King Minos, ruled. The site affords a panoramic view of the Messara Valley, the imposing Ida Mountain range and the Asteroussia Mountains stretching in front of the Libyan Sea. The next visit will be ancient Gortyna, once capital of the old roman prefecture, where the longest coherent legal text of the Dorian’s was found. There you can also see ruins from Roman, Doric and Byzantine times. Then you will take a break at Matala, have free time for lunch and enjoy the crystal-clear water from which, according to the myth, Zeus and Europe emerged. There will be time to visit the famous stone-age caves in the cliffs near the beach. Time Schedule 09:00-18:00 Price 80 ₏ per person Includes bus transfer, English guide, lunch & entrance at Phaestos & Gortyna

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Knossos Palace – Archanes & Wine Tasting Where the Ancient Culture meets God’s Nectar

23.05.2010 Sunday

Minimum Participation 20 persons

The most brilliant Aegean island civilization was the Cretan or Minoan Civilization, which flourished in Crete mainly in the 3rd and 2nd millennium B.C. and took its name from Minos, the legendary king of Knossos. While in other parts of Europe civilization had barely begun to glimmer, the great Minoan kings managed to make Crete a mighty sea power. Wealth and treasures were amassed, which led to the creation of the renowned Cretan palaces of Knossos between 2200 and 1550 B.C., where the arts flourished. The Cretans enjoyed home comforts such as running water, bathtubs and complex plumbing systems. We are heading to the little town of Archanes, which stands on the slopes of low hill. The area produces the best Cretan table grapes and the famous wine. We walk through the narrow lanes with picturesque neo-Classical houses whose balconies and courtyards are like a permanent floral exhibition. We finish our journey with a last visit to a winery and we will visit the production plant, the bottling and labeling area. Then a film will be presented showing the present-day wine production from beginning to the end. A visit to winery is not complete without a wine tasting… Time Schedule 09:00-14:30 Price 57 € per person Includes bus transfer, English guide, entrance at Knossos & wine testing

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Workshop Secretariat The Workshop Secretariat will operate throughout all sessions of the 5th International Hydrocephalus Workshop. ARTION Conferences & Events Att: 5th International Hydrocephalus Workshop 9th km Thessaloniki - Thermi, Thomas Building P.O. Box 60705, GR 57001 Thessaloniki Tel.: +30 2310 250928 (direct line), +30 2310 272275 Fax: +30 2310 272276, +30 2310 277964 E-mail: hydrocephalus10@artion.com.gr Website: www.hydrocephaluscrete2010.gr

Workshop Coordinator Despina Amarantidou

Secretariat – Hotel Accommodation Matina Katsarou

Sponsorship

Marianna Georgitseli

Publications Project Manager Maria Kantziari

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Registration & Hotel Accommodation Form Please complete a separate form per participant (only one accompanying person can be included on the same form) and return it no later than 1 May 2010 by fax or email to: ARTION Conferences & Events Att: 5th International Hydrocephalus Workshop 9th km Thessaloniki - Thermi, Thomas Building P.O. Box 60705, GR 57001 Thessaloniki Tel.: +30 2310 250928 (direct line), +30 2310 272275 Fax: +30 2310 272276, +30 2310 277964 E-mail: hydrocephalus10@artion.com.gr Personal Data (in block letters, in English) Title:

Prof.

First Name:

Dr.                

Mr.

Mrs.

Ms.

Address:

                               

Family Name:

               

City:

Position:

               

Post Code:                

Organization:

               

Country:

               

Tel.:

               

Fax:

               

E-mail:

               

Accompanying Person* Ms.

/Mr.

/Child

First Name                Family Name                *Please contact ARTION Conferences & Events if you have more than one accompanying person.

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Registration Fees Please tick as appropriate

Until 15/3/2010

From 16/3/2010

Full Participant

450 €

500 €

Resident

300 €

350 €

Accompanying Person

300 €

300 €

Free attendance at the 24th Annual Hellenic Congress of Neurosurgery (obligatory registration at Workshop) The registration fee includes the attendance at the Workshop, Workshop material, entrance to the poster sessions and exhibition area as well as coffee breaks, lunches and dinners according to the course programme. Registration fees also cover participation to the 24th Annual Hellenic Congress of Neurosurgery, for those wishing to attend. The accompanying person’s fee includes two tours of the cultural programme of your choice and participation to all social and cultural events.

Dietary Requirements Please indicate any special dietary requirements: Participant

Vegetarian

Other, please specify:

Accompanying person

Vegetarian

Other, please specify:

Special Services: Please let us know if you require any special assistance by attaching a separate sheet outlining your needs.

Hotel Accommodation

Special room rates have been arranged for the participants of the Workshop. Prices are per room per night at the hotel and include buffet breakfast, services and all taxes. Please tick the appropriate rates applicable to the room type you require and fill in the total accommodation cost box. (Minimum stay 3 nights). Arrival (check in) date in Heraklion:                 /05/2010 Departure (check out) date from Heraklion:          /05/2010 Creta Maris Convention & Single BB Golf Resort 

Double BB Triple BB

Suite for Suite for max 2 single use persons

Nights

www.maris.gr 155 €

175 €

250 €

X                                

*Double BB room price is for 2 persons.

2

235 €

280 €

Total in EURO


Flights

If available please complete your flight details below. It will help our airport welcome desk staff to welcome you to Heraklion on Thursday 20 May. If not, please inform us at a later stage. Arrival from:                 Flight Nr.:                 Date:                 Time:                 Departure to:                 Flight Nr.:                 Date:                 Time:                

Participation in the Accompanying Persons’ Cultural Programme (Minimum participation 20 persons) Please select the excursion you wish:

Date

Chania - Rethymno

Friday, 21 May

Price / Persons First & Family Name Person 73€

1 2

               

Phaestos - Gortyna Saturday, 22 May Matala

80€

1 2

               

Knossos - Archanes Sunday, 23 May Wine Testing

57€

1 2

               

                                               

Τwo tours of your choice are included in the accompanying person’s fee.

Post Workshop Tours

If you wish to extend your stay, special day tours from Athens are offered by ARTION Conferences & Events to the participants of the Workshop. Please consult the website of the Workshop for a full description or contact directly the Workshop Secretariat for reservation and any assistance or further information.

Summary of Payment Registration Fee

€               

Hotel Accommodation

€               

Accompanying Persons’ Registration Fee & Cultural Programme Fee

€               

Total Amount Due (EUR)

€               

Method of Payment

Please choose method of payment: Bank transfer to the following bank account: Beneficiary: ARTION Account Nr.: 5212-038-347-344 Swift number: PIRB GRAA IBAN Nr.: GR 24 0172 2120 0052 1203 8347 344 Bank: PIRAEUS BANK, ETHNIKIS ANTISTASEOS BRANCH (2212), THESSALONIKI Please make sure you state your name when transferring your payment and send by fax to ARTION a copy of your bank transfer receipt. Note that all banking costs bear the participant. 3


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Credit Card I duly authorise ARTION Conferences & Events to debit my credit card for the total amount due and settle my debit balance by 31 March 2010. Visa

Card Nr. (digits):                                                                

American Express

Expiration date:        /       (MM/YY)

Mastercard

Cardholders name:                               

The invoice will be issued to The Participant

Passport

                              

The Company

VAT. Nr.

                              

Company Name

                              

Address                                All invoices will be given upon arrival at the Workshop venue unless requested otherwise.

Payment Conditions

Full payment for registration, hotel accommodation & accompanying persons’ fee should reach the Workshop Secretariat no later than 31 March 2010.

Cancellation Policy

Registration 1. Written cancellation received by 31 March 2010. No cancellation fee. 2. Written cancellation received on or after 1 April 2010. No refund. Hotel Accommodation 1. Written cancellation received by 31 March. One night cancellation fee applies. 2. Written cancellation received on or after 1 April 2010. Two nights hotel cancellation fee applies. 3. Written cancellation on or after 1 May 2010 or Non-show. No refund. Cultural Programme 1. Written cancellation received 31 March 2010. No cancellation fee. 2. Written cancellation received on or after 1 April 2010. No refund. All refunds will be processed after 23 July 2010. By signing this form, I                                declare to accept all instructions & conditions for reservations made Date:

                               Signature:

                              

PLEASE RETURN TO ARTION Conferences & Events Fax: +30 2310 277964, +30 2310 272276, Email: hydrocephalus10@artion.com.gr If registered via e-mail and you wish to pay by credit card, please return by fax the last two pages of the registration form with your signature and full name.

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5th International Hydrocephalus Workshop