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Journey of a Cord Blood and/or Cord Tissue Sample The samples arrive. Early each morning, transportation boxes containing the freshly collected umbilical cord blood and/or cord tissue samples are delivered to Future Health Technologies’ facilities in Nottingham. The fully accredited transportation boxes have been specifically designed to comply with EU and IATA regulations, to protect the samples from environmental conditions and maintain the cord blood stem cells in their optimum state prior to processing and isolation of the stem cells

Reception of samples and labelling. On receipt of each sample, the baby’s/parents’ details are double-checked and verified on our database. The contents of the collection kit are carefully examined and recorded. Unique bar coded identification labels are placed on every part of the sample.

Pre – Processing. The cord blood collection bag and/or cord tissue container are cleaned, sterilised and then passed into one of our GMP processing laboratory clean rooms (controlled areas, where outside clothing is not permitted and the air inside is filtered and sterile). All processing takes place within these clean rooms in order to protect the samples from the outside environment during this critical phase. The samples are tracked throughout the subsequent processing stages via their unique bar coded ID labels.

Tel: 0115 967 7707 Future Health Technologies Ltd Fax: 0115 967 7836 www.futurehealth.co.uk e-mail: info@futurehealth.co.uk V4


Journey of a Cord Blood and/or Cord Tissue Sample Processing. Next, the cord blood stem cells and all the other important cells that accompany them, are isolated using latest technology automated cell processing equipment. The cells are placed into a cryopreservation bag. A small sample is removed to check for viability and sterility. A measured amount of cryopreservation medium is added to the cells. The cryopreservation bag is sealed and then it goes to the cryopreservation area.

This is the cryopreservation bag containing the cells prior to freezing. The bag is divided in 2 sections. These can be used together for a transplant but the 20 per cent fraction can also be separated for other applications. There are also a number of smaller sealed portions in the adjoining tube segments which may be used for HLA typing (the unique markers used to match samples between donor and recipient) or other required testing prior to transplantation or other medical applications.

Tel: 0115 967 7707 Future Health Technologies Ltd Fax: 0115 967 7836 www.futurehealth.co.uk e-mail: info@futurehealth.co.uk V4


Journey of a Cord Blood and/or Cord Tissue Sample Cryogenic freezing. The double�wrapped cryopreservation bag is placed into a stainless steel outer protective case. Computer controlled cell freezing equipment slowly cool the samples in a carefully designed way in order to preserve their vitality and prepare them for long term safe keeping. The metal canister containing the frozen cells is placed into a rack in one of the main storage tanks and held in the vapour phase of Liquid Nitrogen – the optimum method for long term cell storage. The exact storage location is recorded on our secure database on the sample record for future traceability and reference.

Long term storage. The large storage tanks each hold around 8,000 samples. They are held within a secure storage area where they are electronically monitored 24 hours a day.

Tel: 0115 967 7707 Future Health Technologies Ltd Fax: 0115 967 7836 www.futurehealth.co.uk e-mail: info@futurehealth.co.uk V4

/Journey-of-a-Cord-Blood-Sample  

http://www.futurehealthbiobank.co.uk/sites/default/files/downloads/Journey-of-a-Cord-Blood-Sample.pdf

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