Center for Biomedical
Innovation and Technology
Yale CBIT Healthcare
HACKATHON
PROGRAM BOOK
FRIDAY, JANUARY 22- SUNDAY, JANUARY 24
Big Data
2021
Real World Evidence Medical Sensors & IoT
Clinical Trials
Economic Forecasting
Epidemiology & Disease Modeling
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Table of Contents 04/05
Welcome
06
Discord / DevPost
07
Team Registration Mentor Genius Bars
08/09/10
Hackathon Schedule
11/12
Keynote Speakers
13/14/15
Project Presentation Project Submission Awards
16/17
Meet the Judges
18/19/20/21/ 22/23/24/25/ 26/27/28/29 Meet the Mentors
30/31 CBIT Committee Sponsors
Zoom link for all scheduled hackathon-wide events: https://zoom.us/meeting/register/tJMldOirqzgtEtOV08jfbzMsqlzzP7Mpxni0
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Welcome!
“I love seeing the multidisciplinary, multigenerational teams working together. It is amazing what can be developed in 24 hours!�
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Dear Participants, Welcome to the 2021 Yale Healthcare Hackathon! The theme this year is Using Big Data & Real World Evidence with proposed tracks including:
Medical Sensors & IoT
Clinial Trials
Economic Forecasting
Epidemiology and Disease Modeling
We are thrilled you are joining us for what will be an intense, productive, and fun weekend. Health and healthcare loom large in our national debate, as does our responsibility to be a global leader in innovative solutions to health challenges. We are delighted to bring people together from across the country as well as from around the world to focus on the most pressing challenges in healthcare. It is a privilege to have this group assembled, and we look forward to hearing your fantastic ideas!
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WHAT IS CBIT? The Yale University Center for Biomedical Innovation & Technology (CBIT) is an interdisciplinary initiative to foster greater innovation in medical technology. It catalyzes biomedical commercialization by educating the next generation of clinical, engineering, and business leaders and by identifying and supporting innovative medical product opportunities.
CBIT LEADERSHIP Mark Saltzman, PhD Co-Founder
Michael K. Dempsey Co-Executive Director
Chris Loose, PhD Co-Executive Director
Margaret Cartiera, PhD Innovation Director
David Rosenthal, MD Clinical Director
Michelle Nantel Operations Manager
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JOIN DISCORD & DEVPOST If you don’t already have one, make an account on https://discord.com/ by following the
directions given on the website. We recommend using @FirstnameLastname as your handle! Join CBIT Discord server using this link: https://discord.gg/y7jEtQrUXt
Announcements Channel: This is where CBIT leadership will make public announcements (about speakers, logistics, timelines, etc).
Help Channel: This is where you can ask logistical questions to CBIT leadership.
Open-discussion Channel: This is an open discussion channel where anyone can ask for advice or provide encouragement to other teams.
Mentor Channels: Live on Jan 23 Each mentor has their own channel. Anyone can chat with the mentors in these channels. Voice calls or Zoom meetings can be arranged individually by team members and/or mentors as needed. A list of our mentors and their areas of expertise is available on page #. Mentor availability will be announced by the CBIT leadership during the Hackathon through the Announcements Channel.
Committee Channel: Private channel for CBIT committee members.
Team Channels: Live on Jan 23 Each team has a private channel. These channels can only be viewed by teammates, mentors, and CBIT leadership.
Join DevPost Go to https://yale-hack-health.devpost.com. Click “Join hackathon”. Log in or make an account by following instructions given.
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TEAM REGISTRATION Each team must complete a single team registration form by Saturday at 11am EST. In this
form, each team will select their preferences for a Genius Bar appointment for Saturday as well as their preferences for a followup session on Sunday. Please remember your randomlyassigned team number given on the form.
Form link will be sent out on Discord #announcements channel.
MENTOR GENIUS BARS The CBIT Genius Bar consists of a small panel of mentors with expertise in Big Data, Business,
Entrepreneurship, Technology, Medicine/Science, Design, and Legal. These mentors will help guide creative processes and challenge business model plans by providing early guidance
and/or fine tuning of a clear idea. They will listen to presentations in its very early stages and provide feedback during a 15 minute appointment on Saturday. Teams will then have an opportunity to fine tune their presentations and present to a mentor panel again on Sunday in time to make adjustments before submitting final presentations to the judges.
See pg.18 for mentor list.
CBIT leadership will send a message in your team channel in Discord to confirm your appointments and assign a Genius Bar. They will also send the Zoom link and remind you when it is your turn.
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EVENT SCHEDULE FRIDAY 01/22
All times in Eastern Standard Time (EST)
Main Zoom Link for Hackathon
Please change zoom name to Discord username.
5:00pm EST
Kick-Off Event: Welcome & Overview 5:30pm
Keynote Speaker: Karen DeSalvo, MD, MPH, MSc 6:00pm
Keynote Speaker: Harlan Krumholz, MD, MS 6:30pm
Pitches If you have a pitch idea to present, please email it to yalehackhealth@gmail.com by Thursday, Jan 21.
7:30pm
Team Formation & Networking. To be done individually.
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– All Teams
– Individual Teams
– Speakers / Fireside chats
SATURDAY 01/23 9:00am EST
See Main Zoom Link
Pitch review + additional pitch ideas 11:00am
Team registration and mentor genius sign-up deadline 12:00pm
Floating mentors available (12-9pm) Mentor genius bar sesssions (2-6pm) See pg.18 for mentor list
1:00pm
Zoom links will be sent in Discord
Mentor Fireside Chats 12:00pm: David Reshef 1:00pm: Marjorie Gomez 2:00pm: Xinxin “Katie” Zhu, MD, PhD, FAMIA 3:00pm: Michael Hund, MBA 5:00pm: Kevin Chen, MD MHS
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SUNDAY 01/24 9:00am EST
Floating mentors available (9-11am) Mentor genius bar sesssions (9-11am) See pg.18 for mentor list
12:00pm
DUE: Final project submissions 3:00pm
Finalist presentations. See pg.14 Judges deliberate 5:00pm
Winners announced & Closing ceremony
See Main Zoom Link
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KEYNOTE SPEAKERS
Karen B. DeSalvo, MD, MPH, MSc CHIEF HEALTH OFFICER AT GOOGLE HEALTH Dr. Karen B. DeSalvo is an Adjunct Professor of Medicine and Population Health at the University of Texas at Austin Dell Medical School and Senior Fellow at the Bipartisan Policy Center. She is a nationally recognized health policy leader working at the intersection of medicine, public health, and information technology to improve the health of people and their communities. DeSalvo was an instrumental leader in the effort to re-engineer healthcare in Louisiana following Hurricane Katrina. This included a multi-sectoral collaborative to drive a community based and focused model grounded in primary care, enabled by health information technology, and supported by a value-based payment. She served as Assistant Secretary for Health (Acting) and National Coordinator for Health Information Technology at the U.S. Department of Health and Human Services in the Obama Administration. While at HHS, she launched Public Health 3.0, a vision for 21st century public health. DeSalvo was previously the New Orleans Health Commissioner. Prior to that role, she was Vice Dean for Community Affairs and Health Policy at Tulane School
of Medicine and Chief of General Internal Medicine and Geriatrics. She is co-convener of the National Alliance to Impact the Social Determinants of Health (NASDOH). She serves as a director on the board of Welltower and is a member of the Verily Life Sciences Advisory Board and a Commissioner on the Medicare Payment Advisory Commission (MedPAC). DeSalvo served on the Humana Board of Directors from 2017 to 2019. She is the current President of the Society of General Internal Medicine and is the Honorary Vice President, United States, for the American Public Health Association. She is a member of the National Academy of Medicine where she serves on the Culture of Health Board. She was a member of the Committee on Integrating Social Needs into Health Care and the NAM/ RWJF Assessing Community engagement in Health and Health Care. She earned her M.D. and M.P.H. from Tulane University, and M.Sc. from the Harvard School of Public Health and was a Robert Wood Johnson Foundation General Physician Faculty Scholar.
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Harlan M. Krumholz, MS, MD DIRECTOR, CENTER FOR OUTCOMES RESEARCH AND EVALUATION (CORE) HAROLD H. HINES, JR. PROFESSOR OF MEDICINE (CARDIOLOGY) AND PROFESSOR IN THE INSTITUTE FOR SOCIAL AND POLICY STUDIES, OF INVESTIGATIVE MEDICINE AND OF PUBLIC HEALTH (HEALTH POLICY) YALE SCHOOL OF MEDICINE Harlan Krumholz is a cardiologist and scientist at Yale University and Yale New Haven Hospital. He is the Harold H. Hines, Jr. Professor of Medicine and director of the Center for Outcomes Research and Evaluation (CORE). He is a leading expert in the science to improve the quality and efficiency of care, reduce disparities, improve integrity in medical research, and avoid wasteful practices. Dr. Krumholz has been honored by membership in the National Academy of Medicine, the Association of American Physicians, and the American Society for Clinical Investigation. He was named a Distinguished Scientist of the American Heart Association and received their Clinical Research Prize. He founded the American Heart Association’s Quality of Care and Outcomes Research Council and their annual conference. He was the founding editor of Circulation: Cardiovascular Quality and Outcomes; founding editor of CardioExchange, a social media site of the publisher of the New England Journal of Medicine; and a founding Governor of the Patient-Centered Outcomes Research Institute. He served as a member of the Advisory Committee to the Director of the National Institutes of Health. Dr. Krumholz received the Friendship Award from the People’s Republic of China in recognition of his collaborative efforts to develop a national cardiovascular research network.
Recent efforts are focused on harnessing the digital transformation in healthcare to accelerate knowledge generation and facilitate the delivery of care aligned with each patient’s needs and preferences. Dr. Krumholz leads the Yale University Open Data Access (YODA) Project, designed to increase access to clinical research data and promote their use to generate new knowledge. He is a co-founder of HugoHealth, a patient-centric platform to engage people as partners in research and facilitate the secure movement of digital health data and co-founder of Refactor Health, an enterprise healthcare AI-augmented data management company. He is a co-founder of medRxiv, a non-profit preprint server for the medical and health sciences. Before joining the Yale faculty in 1992, Dr. Krumholz received a BS (Biology) from Yale, an MD from Harvard Medical School, and a Masters in Health Policy and Management (SM) from the Harvard University School of Public Health. At Yale, he directed the Robert Wood Johnson Foundation Clinical Scholars Program from 19962017 and serves as Director Emeritus of the National Clinician Scholars Program. He was a founding faculty co-director of the Yale Center for Research Computing. Dr. Krumholz has published more than 1000 articles and three books, and has an h-index of almost 200.
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PRESENTATION GUIDE 3 minute pitch + 2 minute Q&A
We recommend ~1 minute: Background and presentation of unmet need ~1 minute: Description of proposed solution ~1 minute: Explanation of business plan
In the interest of time, not all team members need to speak.
JUDGING CRITERIA 20% Health Impact PRACTICE
Clear statement of compelling and unmet healthcare need.
PRACTICE PRACTICE!
20% Innovation Solution demonstrating understanding of clinical and other stakeholder needs.
20% Business Model Business case to justify the investment the product would require.
20% Product Progress in generating data, prototype, or user interface during weekend.
20% Presentation Presentation WOW factor, staying on time, diversity (of skills) of team.
20% 20%
20%
20% 20%
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SUBMITTING PROJECTS All project submissions are due on our DevPost (yale-hack-health.devpost.com) on Sunday, 01/24 at 12:00 PM EST. During submission, you will be required to submit a video (YouTube link) or a narrated Powerpoint presentation explaining and demonstrating your team’s project. Please keep in mind that your videos/presentations should only be a maximum of 3 minutes long. Semifinal judges will review all projects and choose the top 20 to move on to the final round. The final round projects will be announced at start of the finalists presentations at 3pm.
FINALIST PRESENTATIONS 3PM EST We would love to gather all of our final judges and participants in a Zoom meeting to view the top 20 project submissions and celebrate their hard work! The finalists’ pre-recorded presentations will be viewed together (use main Zoom link), followed by a live 2 minute Q&A session to give the final judges an opportunity to ask each team’s members some questions about their project.
Please change your Zoom screen name to begin with your team number (###-name).
We encourage teams to continue working even after the hackathon. Programs and resources to help you continue your project will be available, but ultimately the decision to utilize them is completely up to you and your team.
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AWARDS
Grand Prize $2,500.00
Runner-Up Prize $1,500.00
Honorable Mention $1,000.00
Audience Choice $750.00
LAST YEAR’S GRAND PRIZE WINNER: DIVERSIFI Technology solution to increase mentorship & diversity in the healthcare workforce
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MEET THE FINAL JUDGES
Rob Betiigole, PE, MPPM
Amy C. Justice, MD, PhD
Nitu M. Kashyap, MD
Peter G. Schulam, MD, PhD
Hackathon
Erica S. Spatz, MD, MHS
Sten H. Vermund MD, PhD
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Aracelis Z. Torres, PhD, MPH
MEET THE MENTORS saurabh_awasthi #5447
Saurabh Awasthi Saurabh Awasthi is currently Head of Strategy & Operations at the Global Development Office at Takeda Pharmaceuticals. He has been obsessed with the notion of bending the time and cost curve of drug development for the last several years. It can take more than 10 years and $1 billion to get a drug to market. It’s not sustainable and it doesn’t have to be that way. He works with R&D Leaders to codevelop and implement strategies that would enable a radical reduction in operational cycle times (and thereby costs) by improving business processes, internal capabilities as well as external partnerships. He is particularly interested in the role that technology, especially Artificial Intelligence & Machine Learning, can play across the R&D value chain to improve speed, increase the probability of success, and reduce costs. Before joining the biopharma industry, he was a management consultant and led several R&D transformation initiatives for large-, mid-, and small-tier biopharmacos, Private Equity and Contract Research Organizations (CROs).
FatemaBasrai #7566
Fatema Basrai, MBA Fatema currently serves as the Assistant Director of InnovateHealth Yale and Innovation Manager for the Sustainable Health Initiative at Yale University. In her role, she works with students, faculty, staff and community members to support social ventures in health and education across the globe. She is active in the global health and educational equity community and has presented nationally and locally on panels including those for DreamWeek, The American Association for University Women, and Leadership for Educational Equity. Fatema started her career as a third grade teacher in San Antonio, Texas. In addition to leadership roles in education non-profit organizations, she also served as the Vice Chair for the San Antonio Independent School District’s 2016 Bond Committee which oversaw a $450 million dollar bond and was a founding member of SA RISE, an educational equity community organizing group in South Texas. Fatema was named to the Forbes 30 Under 30 in Education list for 2018 and is dedicated to ensuring educational and health equity for people globally.
SBC #5607
Supriyo B. “SB” Chatterjee, MSc, MBA, MA Supriyo “SB” Chatterjee is a Healthcare entrepreneur & consultant. He has worked for companies like Aetna Healthcare, US Army Medical Corps, UNICEF, Microsoft, & IBM. He is a Connecticut Health Foundation Healthcare Leadership Fellow. He is in the State Healthcare Innovation program and Advisory Council of the State Office of Health Strategy. He received the Microsoft Most Valuable Professional (MVP) award six times. He is a coach/mentor in various Yale healthcare events. He holds graduate degrees in Computer Science, Business, and Economics.
kchenmd #3413
Kevin Chen, MD, MHS Kevin is a physician, health systems scientist, and social entrepreneur. As Director of Design & Evaluation at NYC Health + Hospitals, he develops, implements, and studies interventions to improve health at the largest public healthcare system in the United States. This work includes managing telehealth services and leveraging data to improve access, quality of care, and business operations.
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CBIT Healthcare Hackathon
Big Data
Entrepreneur/Business
Engineer/Tech
Med/Science
Design
Legal
rscreager #0872
Richard S. Creager, PhD Richard has more than 35 years of experience in the in vitro diagnostics industry. Currently, Dr. Creager is the co-founder of NaviDx LLC, a management consultant firm. He also is a business consultant for the SBDC@UCI Beall Applied Innovation and an advisor to the National Institutes of Health (NIH) RADx program for SARS-CoV-2. Previously, Richard was SVP Molecular Diagnostics and Chief Science Officer for Beckman Coulter. He currently serves on the board of directors for the 1for2 education foundation, OnRamp Bioinformatics, and Ubiquitome. Richard has a B.S. from Muhlenberg College, a M.S. from Duquesne University, and a Ph.D. from the University of Pittsburgh School of Medicine.
Jesus dV #8346
Jesus del Valle Rosales, PhD Jesus is originally from Havana, Cuba. A Physicist from the Technical University of Dresden, Biology PhD at the Max Planck Institute / Free University Berlin, he has worked in Life Sciences for 20+ years. At Bayer he leads the R&D Open Innovation Stranger Things Team. He founded the G4A digital health accelerator in 2013, the global STEM4Health community, 15,000+ members, and recently co-founded AcceleRed, a company building project. One of his passions is bringing together startups’ culture & technology with Bayer’s experience. Twitter: https://twitter.com/yeysus. LinkedIn: https://www. linkedin.com/in/yeysus/.
Jun Deng #6569
Jun Deng, PhD Dr. Jun Deng is a Professor at Department of Therapeutic Radiology of Yale Medical School. Dr. Deng obtained his PhD from University of Virginia and finished his postdoctoral fellowship at Stanford University. Currently with funding from NIH, NSF and DOE, Dr. Deng’s research has been focused on artificial intelligence, machine learning, big data, and medical imaging for cancer early detection and prevention, real-time clinical decision support, as well as digital twin modeling of cancer patients.
pdicapua #8623
Paul DiCapua, MD, MBA Dr. Di Capua is a board certified internist seeking to build health systems designed to sustainably meet the needs of patients and their communities. He believes these systems will need to lean on technology for scale, and need to be decentralized for “last mile” implementation. He is interested in using data science, design principles, and organizational behavior to make it easy to be recipient and provider of compassionate and humane care. He was most recently the National Medical Director at Aspire Health.
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Entrepreneur/Business
Engineer/Tech
Med/Science
Design
Legal
doolittleben #8548
Benjamin R. Doolittle, MD, MDIV Dr. Doolittle is the residency program director and clinic director for Yale’s medicine-pediatrics residency. He has been involved in several panel management projects, medical device and design, and quality improvement.
FabyF #9227
Blanca Fabiola Fajardo Fregoso, MD, PhD Clinical scientist seeking to create a team for the development of translational and evidence-based solutions to health problems. Clinical research investigator and doctoral experience in biomedical science with project management proficiencies. Curious and excited about the emerging digital transformation and personalized medicine. Fregoso is also an advocate for increasing the presence of women in science, technology, engineering, and math.
helenefevrier #3918
Helene Fevrier, MSPH Helene Fevrier is a data scientist with over 5 years of real-world evidence experience. She has been working at Verana Health, where she collaborates with industry partners to design and analyze epidemiological studies with a focus in ophthalmology. Prior to joining Verana Health, her work at Kaiser Permanente focused on analyses and applied research studies with an operational impact. Helene holds a Masters of Science in Public Health from Rollins School of Public Health.
ewf5012 #3159
Erick W. Froede Erick Froede wakes up every day driven to build innovative digital products that have the power to change lives for the better. His experience spans the entire product lifecycle and is a unique mix of software / hardware, international / domestic, and high-growth startup / large corporate. “If you’re on a mission to change healthcare, let’s talk!”
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Ashveena Gajeelee Ashveena Gajeelee is a public policy specialist with interdisciplinary experience in financial services and global health.Ashveena has a strong experience in working with governments and companies on a global scale to implement reforms and change in times of crisis. She is a collaborator of the Global Access in Action at Harvard University. Ashveena supports GAiA’s action-oriented research which focuses on promoting access to medicines and the use of technology/AI in healthcare. She is also an adaptive leadership coach and is a teaching fellow at the Harvard Kennedy School. Ashveena is a member of the Harvard Kennedy School Alumni Board and holds degrees from the Harvard Kennedy School, the Graduate Institute of Geneva and the Ecole Nationale d’Administration, France.
mayonesa #0291
Marjorie Gomez Marjorie Gomez has a multicultural background with vast experience in Engineering, Equine Business, Accounting, and IT. Due to her repertoire on Innovation Methods, she is continuously engaged in mentoring and co-organizing Universities’ Hackathons while supporting the initiative #MoreScience4Berlin. Her Massive Transformative Purpose is building future women leaders in low income communities. Therefore, she is an Inclusion and Diversity Activist.
rgueorguieva #7687
Ralitza Gueorguieva, PhD Gueorguieva obtained her Ph.D. in Statistics from University of Florida in 1999 and has been a faculty member of the Department of Biostatistics at Yale University School of Public Health since 2000. Her research interests are in methodological development of models for longitudinal data and outcomes of different types, assessment of risk and the application of innovative statistical approaches for clinical trials data. Dr. Gueorguieva is collaborating extensively on clinical trials and observational studies in psychiatry and mental health.
irahall9 #5447
Ira M. Hall, PhD Ira Hall is a Professor of Genetics and Director of the Center for Genomic Health at Yale University School of Medicine. He runs an academic research laboratory focused on application of genome sequencing and computational approaches to understand human phenotypic variation disease.
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S-HAY-YALE #6247
Sam Hayek Sam Hayek is a mechanical engineer, banker, organizational consultant and coach. He pursued a career in finance, having earned an MBA from The Wharton School. As a banker, Mr. Hayek led professional teams focused on financing and advising corporate and government clients throughout the United States, Canada, Western Europe, and South America. In addition to leading a structured finance consultancy team, he oversaw numerous business improvement and data/Info management projects. In 2010 Sam Hayek pursued a career transition into organizational coaching and consulting. His practice focused on leadership and collaboration across-cultures, as well as business improvement and organizational agility in light of technological shifts and accelerating product life cycles. He also earned a certification in career and personal coaching from NYU.
Yusuf2021 #1157
Yusuf Henriques Yusuf Henriques is the CEO and co-founder of CodeClear Ventures Inc. CodeClear is enabling a new multiplex platform of in-vitro diagnostics and rapid pathogen detection tests for SARS-CoV-2 and other infectious diseases using quantum dots chemistries. Before CodeClear, Henriques founded TruGenomix Health Inc., an emerging precision genomics behavioral health company harnessing the power of genomics to improve risk prediction and diagnosis of Post-Traumatic Stress Disorder (PTSD). The PTSD genomic assay (TruGen-1) that he developed used exclusive patented technology provided by Icahn School of Medicine at Mount Sinai (ISMMS)and Max Planck Institute (MPI) and is now being piloted at the Department of Veteran Affairs (VA)hospitals nationwide to address the high rate of suicides in the veteran and active-duty population. Through collaboration with TruGenomix, the VA hopes to one day be able to identify genetic markers associated with post-traumatic stress disorder and suicidal tendencies. Finding such markers may allow VA clinicians to determine which Veterans may be predisposed or at increased risk for such conditions. Mr. Henriques earned a Bachelor of Science in Biochemistry from Howard University, graduating magna cum laude. He enjoys soccer, reading and listening to reggae music.
allenlh #5452
Allen L. Hsiao, MD, FAAP Allen Hsiao, MD, is Chief Medical Information Officer (CMIO), Yale New Haven Health and Yale School of Medicine. In this role, Dr. Hsiao leads a team of physician informaticians responsible for medical leadership of the electronic health record system (EHR) and supporting information technology systems to provide the functionality, clinical decision support, and innovation needed to deliver the best healthcare possible. He also oversees the Joint Data Analytics Team (JDAT), a the reporting and analytics for the System and the School, supporting operational, clinical, and research reporting and data needs.
MichaelPHund #0088
Michael Hund, MBA Michael Hund is the CEO of EB Research Partnership, a game-changing medical research organization dedicated to curing the life-threatening genetic skin disease Epidermolysis Bullosa (EB) and pioneering the innovative business model of Venture Philanthropy. Michael has spent his career dedicated to transforming healthcare. He received his BA in Philosophy from the University of Kansas, CORe credential from Harvard Business School, and MBA from the Yale School of Management.
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Hackathon Big Data
Entrepreneur/Business
Engineer/Tech
Med/Science
Design
Legal
Smita Krishnaswamy #6998
Kratz #5067
Val Kratzman, MHCA, MBA Mr. Kratzman is an international business and healthcare strategist. He has over 35 years’ experience working with start-ups and Fortune 100 companies. Val launched new medical and scientific products and has been active in M&A transactions. Recently, he designed and developed a US based digital health ecosystem – 4 health systems, 11 VCs, and a pool of 65 business and clinical mentors – to accelerate the commercialization of Nordic companies. Mr. Kratzman is a graduate of the Wharton Business School and completed his graduate studies in Health Care Administration at George Washington University.
Smita Krishnaswamy, PhD Smita Krishnaswamy is an Associate professor in Genetics and Computer Science. She is affiliated with the applied math program, computational biology program, Yale Center for Biomedical Data Science and Yale Cancer Center. Her lab works on the development of machine learning techniques to analyze high dimensional high throughput biomedical data. Her focus is on unsupervised machine learning methods, specifically manifold learning, topological and deep learning techniques for detecting structure and patterns in data. She has developed algorithms for non-linear dimensionality reduction and visualization, learning data geometry, denoising, imputation, inference of multi-granular structure, and inference of feature networks from big data. Her group has applied these techniques to many data types such as single cell RNA-sequencing, mass cytometry, electronic health record, and connectomic data from a variety of systems. Specific application areas include immunology, immunotherapy, cancer, neuroscience, developmental biology and health outcomes. Smita has a Ph.D. in Computer Science and Engineering from the University of Michigan.
Frankkuch #5079
Frank Kuchinski Frank Kuchinski is a systems thinker and a technical program manager who works with startups and large organizations to rethink and simplify their product development and management processes so they can build products faster and deliver a great customer experience. His approach is to use the best parts of lean startup, design thinking, and Kaizen. His industry experience is in: IoT, artificial intelligence, healthcare, brokerage, finance, insurance, edtech, cleantech and behavioral science.
sonya.li #6490
Sonya Li Sonya is a member of the commercial team at Verana Health, where she oversees RWE partnerships with life science companies. She leads research- and regulatory- grade ophthalmology studies that leverage electronic health record registries. Prior to Verana, Sonya was at ClearView Healthcare Partners, a life sciences consultancy. She specialized in market access and evidence generation for rare diseases. She lives in NYC and enjoys running and scuba diving.
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CBIT Healthcare
Entrepreneur/Business
Engineer/Tech
Med/Science
Design
Legal
Ming #4474
MingDe Lin, PhD MingDe Lin, Ph.D., is the Director, Clinical Research North America for Visage Imaging, Inc., to oversee and direct academic-industry research partnerships, especially around Artificial Intelligence and is the liaison with clinical collaborators to translate ideas to products that improve patient care. As Adjunct Assistant Professor, Department of Radiology and Biomedical Imaging, Yale University School of Medicine, Dr. Lin is directly involved in research to develop better ways to treat patients with liver cancer and is also an advisor for Yale’s chapter of the Tau Beta Pi engineering honor society.
elolis #2740
El Lolis El Lolis is an Associate Director at Yale University with experience managing a diverse portfolio of IT efforts toward advancing research, medical, compliance, teaching and learning, and administrative initiatives. With over 10 years of experience in higher education, in addition to her start-up, financial and corporate experience, El brings a strategic and comprehensive approach to idea development and problem solving. El also holds MS in Management of Technology and BSE degrees.
lousk #9825
Shaoke Lou, PhD Shaoke Lou, Associate Research Scientist in Computational Biology and Bioinformatics. He has a multidisciplinary background with a B.S. in Chemistry, an M.S. in Biochemistry and Molecular Biology, and a PhD in Computer Science and Engineering. During his PhD study, he mainly worked on the development of read-mapping algorithms, next-generation sequencing data analysis, data mining and statistics modeling. In the Gerstein Lab at Yale University, his research focuses on developing statistical tools and machine learning algorithms to understand microbiome-host interactions, predicting the effect of mutations, and studying the 3d genome and regulatory network.
RRMont #0070
Ruth R. Montgomery, PhD Ruth R. Montgomery is Professor of Internal Medicine researching individual immune differences that lead to divergent clinical outcomes. She works with the Human Immunology Project Consortium (HIPC) to profile the immune system and construct a comprehensive, centralized database for use by the greater scientific community. Dr. Montgomery’s work is notable for her use of primary human cells and novel technology and she collaborates actively in computational modeling of immune responses.
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Hackathon
Michael Murray, MD
lpusztai NewHaven20201
TBA
Dr. Michael Murray is a physician trained in internal medicine, infectious diseases, and medical genetics. Prior to coming to Yale in 2018, He set up a program at Geisinger Health system in Pennsylvania, to screen a group of 200,000 volunteers for genomic risk of cancer and heart disease. Those with these risks were then placed in the care of healthcare providers who could help them manage this risk. We’re launching a similar program at Yale.
Lajos Pusztai, MD, DPhil Dr Pusztai is Professor of Medicine at Yale University, Director of Breast Cancer Translational Research and CoDirector of the Yale Cancer Center Genomics Genetics and Epigenetics Program. He is also Chair of the Breast Cancer Research Committee of the Southwest Oncology Group (SWOG). Dr. Pusztai received his medical degree from the Semmelweis University of Medicine in Budapest, and his D.Phil. degree from the University of Oxford in England. His research group has made important contributions to establish that estrogen receptor-positive andnegative breast cancers have fundamentally different molecular, clinical and epidemiological characteristics. He has been a pioneer in evaluating gene expression profiling as a diagnostic technology to predict chemotherapy and endocrine therapy sensitivity and have shown that different biological processes are involved in determining the prognosis and treatment response in different breast cancer subtypes. He made important contributions to clarify the clinical value of preoperative (neoadjuvant) chemotherapy in different breast cancer subtypes. Dr Pusztai is also principal investigator of several clinical trials investigating new drugs, including immunotherapies for breast cancer. He has published over 300 scientific manuscripts in high impact medical journals including the NEJM, JAMA, Journal of Clinical Oncology, Nature Biotechnology, PNAS, Lancet Oncology and JNCI. He is among the top 1% most highly cited investigators in clinical medicine according to a 2015 Thomson Reuters report. He is member of the Scientific Advisory Board of the Breast Cancer Research Foundation and a Susan Komen Scholar.
bgr #2919
Brendan Reilly Brendan Reilly is a scientist, engineer, and angel investor working in the greater New York area. He has been an adjunct instructor for the I-CORPS program. He has worked in medical research (lab bench), clinical medicine, investment banking, and many areas of computer science and engineering. He was a Visiting Investigator at MIT in the joint program at Woods Hole Oceanographic Institution.
rajsadhu #8823
Rajendra Sadhu Mr.Rajendra Sadhu is the CEO & VP Technology of VESAG Health Inc a leader in mobile & electronic communication products & services. He has been associated with wireless and medical Industry for long and has pioneered the concept of M-health technology in the world. He holds 22 patents in remote health monitoring, IOT, connected car technologies. He launched first IOT enabled cellular medical smart watch in 2010.
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wschulz #3048
Wade L. Schulz, MD, PhD Dr. Schulz is an Assistant Professor of Laboratory Medicine and computational health care researcher at Yale School of Medicine. He received his PhD in Microbiology, Immunology, and Cancer Biology and MD from the University of Minnesota. He is the Director of Informatics for the Department of Laboratory Medicine, Director of the CORE Center for Computational Health, and Medical Director of Data Science for Yale New Haven Health System. Dr. Schulz has over 20 years’ experience in software development with a focus on enterprise system architecture and has a research interests in the management of large, biomedical data sets and the use of real-world data for predictive modeling. At Yale, he has led the implementation of a distributed data analysis and predictive modeling platform, for which he received the Data Summit IBM Cognitive Honors award. Other projects within his research group include computational phenotyping and the development of clinical prescriptive models for precision medicine initiatives. His clinical areas of expertise include molecular diagnostics and transfusion medicine, where he has ongoing work assessing the use, safety, and efficacy of pathogen-reduced blood products.
chhaya #0348
Chhaya Shadra, MS Chhaya Shadra is an epidemiologist-informatician bringing her deep understanding of systems engineering and user workflow, to healthtech startups. Her recent work has focused on product development, architecture, data modeling, content harmonization, and algorithm development for integrated precision research data platforms sourced from EHR, claims, pharmacy, and medical device data. These platforms are currently being used by pharmaceutical companies in regulatory filings, health economic outcomes research(HEOR) and comparative effectiveness research(CER). Ms. Shadra’s architectural designs ensure interoperability of these custom datasets with standard CDMs like; i2b2, OMOP, Sentinel and PCORnet. The recent shift in focus of the FDA towards improved usage of real world datasets in the drug approval process makes Ms. Shadra’s work extremely relevant to the current healthcare landscape. Ms. Shadra has contributed to informatics and analytic engines at health tech startups like Converge Health by Deloitte, Humedica by Optum and Flatiron Health.
smjorge22 #9364
Jorge Soto Jorge Soto is the co-founder and was the chief technology officer of Miroculus, a biotechnology company that seeks to democratize access to complex molecular tests for treatment and prevention of diseases. Jorge founded Miroculus with the vision of reducing the entry barrier in cost, development, complexity, and increasing access to genetic sequencing, synthetic biology, and genetic editing to help advance science and improve lives.
DStern #1072
David F. Stern, PhD David F. Stern has a career-long commitment to understanding cancer and promoting therapeutic development. His research is focused on EGF family growth factors and receptors in malignant transformation, and more generally on therapeutic targeting of cancer signaling processes including DNA damage signaling. He has a clinical focus on solid tumors, especially breast cancer and melanoma.
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Hackathon
Big Data
Entrepreneur/Business
Engineer/Tech
Med/Science
Design
Legal
Madwilson #1640
Madeline Wilson Madeline Wilson is the Chief Quality Officer for Yale Health, with responsibility for patient safety and quality improvement; information technology and clinical informatics; and population health. Most recently, she lead the university’s COVID-19 Testing and Tracing Committee and is currently collaborating on efforts to provide vaccine to the Yale Community. Throughout her career, she has sought to improve systems to enhance care for patients, and the work experience for clinicians.
kwood #3578
Kevin Wood, MS Kevin Wood is a data scientist who specializes in real world data and clinical analytics. He has spent over 5 years designing, developing, and executing projects and products for clinical benchmarking, clinical trial acceleration, market research, and other RWE use cases with expertise in Ophthalmology. He works at Verana Health to provide custom data projects and products to life science companies to accelerate drug and device developments.
cameron.yick #4493
Cameron Yick Cameron builds analytics tools for problem-solving with cloud infrastructure data, and occasionally writes/gives talks about data visualization. Previously, he worked as a data engineer using public data to build credit risk assessment pipelines. This is his 7th year of hackathons.
KatieZhu #7565
Xinxin “Katie” Zhu, MD, PhD, FAMIA Dr. Zhu is the executive director for the Center for Biomedical Data Science who brings cross-industry experience to academia. Prior to joining Yale, Dr. Zhu served as an Industry Advisory Board member of the Center for Advanced Technology at Columbia University, physician scientist lead at IBM Watson Research Center, associate medical director at Pfizer, and clinical project manager at Philips. She also worked on informatics projects at the U.S. Department of Veterans Affairs through Kforce Government Solutions where she served as Chief Medical Info Officer. In addition to her medical training, she also received her Ph.D. in Biomedical Informatics from Columbia University. She serves as the Co-Chair for the American Medical Informatics Association’s Global Health Informatics Working Group and VP of Membership for the Consumer and Pervasive Health Informatics Working Group. She has 13 issued patents.
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ADDITIONAL MENTORS Richard Campos, MBB, PhD Currently leading the commercialization of Passplot, an embedded, collaborative, mobile first way to enable data fluency for digital enterprises by empowering employees with smart, fast analytics workflows. Richard’s has delivered programs and solutions in prior product and services development at Philips NV, Stryker, and Medtronic. He earned a PhD in Applied Physics at Columbia University, and a Master Black Belt in Lean and Six Sigma business process improvement. Prior Yale Hack Health participant and 2nd place finisher/MIT prize winner (2016). Mentor at Yale Hack Health (2018) and MIT Grand Hack (2017). Expertise in business data analysis and design of products and services for healthcare and electronics industries.
Douglas Berv, MD Dr. Douglas Berv is a psychiatrist practicing psychopharmacology with special interests in mood disorders, PTSD, and head injury. He practices in a small psychiatric group practice, and he teaches at the Yale School of Medicine. They subspecialize in Bipolar Disorders. He has mentored at the last four Yale CBIT Healthcare Hackthons.
Maen Abou Ziki, MD Since medical school, Dr. Abou Ziki has been involved in genetic medicine research with projects encompassing genomics and gene therapy. His current projects include studying genetic modifiers for atherosclerotic coronary artery disease, and arrhythmogenic conditions such as long QT syndrome and heart block. With a focus on cardiovascular genetics, Dr. Abou Ziki’s research will contribute towards better screening and cardiovascular risk stratification, in addition to advancing our molecular understanding of disease pathways.
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Hackathon
Big Data
Entrepreneur/Business
Engineer/Tech
Med/Science
Design
Legal
Patrick Smith Dr. Smith has over 17 years of global drug development experience. Working across all phases of development, he has particular expertise in infectious diseases, oncology, and inflammation, including significant experience with novel early development program design, and applying modeling and simulation to solve critical development problems. As a co-founder of d3 Medicine (now Certara), Dr. Smith has led many development and due diligence projects for clients ranging from pre-clinical development/IND strategy, design and execution of entry-into-human and proof of concept studies, design and implementation of modeling and simulation strategies, and crafting clinical pharmacology and clinical development plans. He has extensive clinical development experience globally, and has interacted with all major health authorities. Dr. Smith was the US Site Head for Clinical Pharmacology for Roche, and a member of key corporate governance committees defining disease area and portfolio strategy. He served as an Associate Professor at the University at Buffalo School of Pharmacy and Roswell Park Cancer Institute. He obtained his PharmD degree from UCSF, and completed a clinical residency at Duke University Medical Center. Dr. Smith currently holds a Research Professor appointment at the University at Buffalo School of Pharmacy, and has authored more than 100 peer reviewed publications in journals including The Lancet and New England Journal of Medicine.
Kiliana Suzart-Woischnik, MD, MPH Kiliana S-W #9793
Medical doctor specialized in Pediatrics at the Federal University Bahia, Brazil, with Master of Public Health from University Ulm, Germany, at Bayer since 2008. Expertise in Epidemiology, Clinical Trials, Real-World-Evidence Generation using Bigdata and Pharmacovigilance in various areas including Cardiology, Digital Health, Infections Diseases. Before Bayer I worked in clinical research at the University of Miami –School of Medicine, USA, and in project management at a middle-sized German CRO, totaling 20 years of experience in clinical research & development and pharmaceutical industry.
Samah Fodeh-Jarad, PhD
Samah Fodeh-Jared PhD
Dr. Fodeh seeks to develop innovative methodologies to address challenging problems in healthcare and biomedical informatics. Her focus is the analysis of exceedingly large data sets; especially those that arise in the application areas of text mining, information retrieval and extraction, machine learning and deep learning. She is interested in developing algorithms that combine multiple data modalities for central tasks such as prediction and clustering of healthcare and social media data.
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CBIT COMMITTEE Avertising & Outreach Michelle Nantel
Sophie Edelstein
Lynne Kim
Molly Bucklin
Ellie Gabriel
Patricia Xu
Irene Pak
Brett Gu
Kerui Yang
Sami Elrazky
AnMei Little
Indira Flores
Kristof Toth
Logistics
Mentors & Judges Jodi Canapp
Emma McKinney
Jonathan Wu
Hema Laksh
Sawyer Newman
Eric Youshao
Jenny Mao
Darrell Pona
Hackathon
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SPONSORS Current Sponsors
Past Sponsors
Contact Us Center for Biomedical Innovation and Technology Yale School of Medicine 310 Cedar Street, BML238 New Haven, CT 06519
https://medicine.yale.edu/cbit/ yalehackhealth.org cbit@yale.edu
2021