signal
signals
DNA
DNA
S
S
η
nucleotides
TC
signal
m− RNA
EX
S ξ charged t−RNA
t−RNA
TL
PR
PR
PR
PR
Figure 9.5 Composition of higher structured modeling objects. Elementary modeling objects are linked to a submodel describing gene expression (left). The aggregated model is assigned the representation given on the right hand side.
THE VIRTUAL BIOLOGICAL LABORATORY: AN OUTLINE
One main purpose of the Virtual Biological Laboratory is to enable computer experiments with cellular systems in analogy to experiments carried out with real biological systems in the laboratory. Applications include the quantitative and qualitative analysis of overall behaviour, systematic design of functional units by genetic modifications and the systematic planning of real laboratory experiments. The Virtual Biological Laboratory has to integrate mathematical models with a sound biological background and methods for data storage, computer-aided modeling, simulation and model analysis in a software tool (Fig. 9.6). Accordingly, the development of such a tool requires the close cooperation of biologists, information scientists and system scientists.
Virtual Databases Biological Laboratory Modeling
Quantitative Measurement
Biology
Hypotheses
Models of biological functional units
Genetic Modification Analysis
tool
Information Sciences
Visualization
Synthesis
Modeling Concept
Systems Sciences Figure 9.6 Elements to be integrated into a Virtual Biological Laboratory.
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