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1.GW 501516/Cardarine Basic information
Cardarine (GW-501516) is drug that binds to the PPAR receptor. It was first created by Glaxo Smith Kline and Ligand Pharmaceuticals in 1992. It was discovered that Cardarine, when binding to the PPAR receptor, recruits what is called the coactivator PGC-1αenzyme, which then increases the expression of genes involved in the expenditure of energy. Rats treated with Cardarine were shown to have increased fatty acid metabolism and increased protection against obesity from eating a bad diet, as well as an increased protection from type-2 diabetes. In another study on Rhesus monkeys, cardarine was shown to increase HDL (good cholesterol) and decrease LDL (bad cholesterol). Reasons for this effect appeared to be caused by an increased expression of the cholesterol transporter ABCA1. In other words, cardarine activates the same genetic pathways that are involved in exercise. In addition, cardarine was studied for use in treating cardio disease before its development was halted in 2007.
2.What is Cardarine Used for?
Cardarine is great for pretty much everything! Incredible endurance benefits from it are probably the most prominent reason to use this product. Not only has it proven to increase endurance in scientific studies, but when you use it for yourself you’d see that the results are nothing short of amazing! If you’re a cardio junkie or just like getting lean, it increase your run times. Your weight lifting sessions will be extended further, you’ll feel energized longer and ultimately get a lot more work done before you walk out of the gym every day.
Of course, fat loss is at the top of the list of reasons why many people love Cardarine so much. Striations and veins get more noticeable and your journey to fat loss becomes a lot easier, without the catabolic effects that most fat burners and drugs can have while trimming down. Fat loss from cardarine is a 2
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