National Institute of Science and Technology for Health Technology Evaluation (IATS) Management committee Flávio Danni Fuchs (Coordinator) Carisi Anne Polanczyk (Vice-coordinator) Sandra Cristina Pereira Costa Fuchs Leila Beltrami Moreira Bruce Bartholow Duncan Celina Maria Turchi Martelli Denizar Vianna Araújo Hillegonda Maria Dutilh Novaes Antonio Luiz Pinho Ribeiro Main researchers Ricardo Ximenes, Demócrito Vidal de Miranda Filho, Maria Cynthia Braga, Maria de Fatima Pessoa Militao de Albuquerque, Ulisses Ramos Montarroyos, Noêmia Teixeira de Siqueira Filha, Celina Martelli, Ana Lúcia Andrade, Cristiana Maria Toscano Soares, Paulo Moacir de Oliveira Campoli, Marília Turchi, Ruth Minamisava, Vicente Porfírio Pessoa Júnior, Antonio Oliveira Pinho , Bruno Ramos Nascimento, Gerusa Maria Figueiredo, Lucas Lodi Junqueira, Silvana Marcia Kelles, Denizar Araújo Vianna , Luciana Bahia , Camila Pepe Ribeiro de Souza, Vanessa Damázio Teich, Maria Novaes , Ana Soledade Graeff Martins, Jorge Luis Padovan , Laura Andrade Lagôa Nóbrega, Otávio Berwanger, Paola Zucchi, Regina Célia Moreira, Marcos Ferraz, Sandra Costa Fuchs, Leila Moreira, Airton Stein, Erno Harzheim, Giácomo Balbinotto Neto, José Roberto Goldim , Luis Eduardo Paim Rohde , Mario Henrique Osanai, Paulo Dornelles Picon , Ricardo de Souza Kuchenbecker , Rodrigo Ribeiro , Sheila Araujo Teles , Luciane Nascimento Cruz Main research topics The research agenda was prepared on the basis of the socio-sanitary requirements of the Brazilian population and the expertise of the centers of IATS. As such, the areas of investigation in HTA include cardiovascular disease, diabetes, hypertension, infectious diseases, including HIV/ AIDS, hepatitis, malaria, vaccines. The methods of investigation and the correspondent reports include primary research (clinical trials, as the PREVER study and cohorts, as the ELSA study, and cross-sectional surveys), reviews, systematic reviews, meta-analyses, health economics, tele medicine and ethics. Most projects have additional funding, but are conducted under the perspective of HTA. Summary of achievements and perspectives Currently IATS hás 77 investigators from nine Institutions presented above. In addition to the investigations on the way, the main activity of the Institute was oriented to the preparation of investigators and collaborators of IATS. Courses of management of STATA and TreeAgee and of metaanalysis were offered. The Seminar of Health Economics and the Scholl of Advanced Studies were the mains initiatives. The first, led by CPES-São Paulo, is already a traditional seminar and was supported by IATS both in financial support and in the participation of IATS investigators. The School of Advanced Studies took place in Porto Alegre between June
28 and July 2nd. A total of 105 participants, including 4 international speakers (David Banta, França, Joseph Mathew, Anushua Sinha, EUA, Ursula Rochau, Áustria), IATS investigators and graduate students participated. Seminars and conferences addressed methodological issues in systematic reviews, meta-analyses, primary research, modeling, economics and ethics. Proposals of transference of HTA technologies to the administrative and clinical settings were specifically presented and discussed. The Seminar was also funded by CAPES. A detailed report of the Seminar is being prepared. Investigations in collaboration between centers and consultation to governmental institutions and health services have been provided. The site of IATS has regularly presented analytical appraisals of the scientific literature and occasionally has granted access to original contributions of the investigators of the IATS. Main publications Fonseca MF, Araújo GT, Araújo DV. Cost Effectiveness of Peginterferon Alfa-2b Combined with Ribavirin for the Treatment of Chronic Hepatitis C in Brazil. The Brazilian Journal of Infectious Diseases 2009;13 (3):191-199. Ribeiro RA, Stella SF, Camey SA, Zimerman LI, Pimentel M, Rohde LE, Polanczyk CA. Cost-Effectiveness of Implantable Cardioverter-Defibrillators in Brazil: Primary Prevention Analysis in the Public Sector. Value Health. 2009 Sep 2. Esmeralci Ferreira1-5, Denizar Vianna Araújo., Vitor Manuel Pereira Azevedo5, Cyro Vargues Rodrigues2,4,Alcides Ferreira Jr.2,4, Camillo de Lellis Junqueira4, José Geraldo de Castro Amino5, Mara Lucia Farias3,Antonio Farias Neto3, Denilson Campos de Albuquerque. Análise de Custo-Efetividade dos Stents Farmacológicos e não Farmacológicos na Doença Coronariana. Arq Bras Cardiol 2010; 94(3): 306-312 Flávio Danni Fuchs.Corporate influence over planning and presentation of clinical trials: beauty and the beast. Expert Rev. Cardiovasc. Ther. 2010; 8(1), 7–9. Glaucia Vespa, Dagna O. Constenla, Camila Pepe, Marco Aurélio Safadi, Eitan Berezin, José Cássio de Moraes, Carlos Alberto Herrerias de Campos, Denizar Vianna Araujo, and Ana Lucia S. S. de Andrade. Estimating the cost-effectiveness of pneumococcal conjugate vaccination in Brazil. Rev Panam Salud Publica. 2009;26(6):518–28. Vanni T, Luz PM, Ribeiro RA, Novaes HM, Polanczyk CA. Economic evaluation in health: applications in infectious diseases. Cad Saúde Pública. 2009;25(12):2543-52. Contacts Juliana Juk Ramiro Barcelos, 2350 – prédio 21 contato@iats.com.br www.iats.com.br
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