SHARED RESOURCES, SHARED SUCCESSES 20
From the start, Sanford-Burnham recognized that investigators would need the Institute’s help accessing state-of-the-art instrumentation and facilities that no individual lab could afford on its own. Today, Sanford-Burnham’s NCI Cancer Center Support Grant allows the Institute to purchase and maintain instrumentation and to subsidize the operation of 20 of the Institute’s 34 core facilities, each offering valuable technology, resources, and expertise. Most facilities also provide services to non-profit and for-profit investigators outside the Institute. Here are just a few examples.
Dr. Craig Hauser Associate Director, Shared Resources
Animal Resources
Cell Analysis and Histopathology
Structural Biology
Sanford-Burnham’s AAALACaccredited animal facility allows investigators to better understand the factors involved in cancer susceptibility, growth, and spread, and to test experimental treatments to defeat cancer.
In the cellular imaging facility, access to a wide variety of microscopes, including fluorescence and confocal systems and a transmission electron microscope, allows researchers to observe cancer on a cellular level.
The structural biology facility allows researchers to probe protein structures to better understand how their activities might help or hinder cancer and how they may be targeted by more specific cancer therapies.
Genomics
Proteomics
Bioinformatics
Experts in our genomics facilities can analyze the status of nearly every gene in a cell, helping investigators address the roles genes play in keeping cancer at bay and how those genes can malfunction.
Researchers use our proteomics facilities to measure which proteins are being expressed within cells. A protein that is overexpressed in a cancer cell may be a marker, allowing earlier diagnosis, or a target for a new treatment.
Our bioinformatics facilities help make sense of the vast amounts of data produced by highthroughput experiments, using sophisticated tools to better understand the biological and medical significance.
shared scientific core facilities
Access the full list at sanfordburnham.org/SharedResources 8