Medicine
Group of people or individuals who are recommended to preserve stem cells A decision for the preservation of the umbilical cord stem cells of a newborn is of particular importance for the following groups: family history of malignant diseases, blood diseases, diseases treated with the stem cell transplantations; couples of different nations because of lower chances for finding a compatible donor in case of need; and pregnant women after artificial insemination or in vitro fertilisation with the use of donated sperm or ovum. The above categories are treated as families with a high risk and therefore recommendations for them are more rigorous, although preserving the umbilical cord stem cells as a procedure is highly recommended for every family which is expecting a baby. In order to help families in need, Cryo-Save in Macedonia for three years has been running a campaign for free family donations, and more than 16 families who have a member who is suffering or had suffered from disease that can be treated with the stem cells have gotten a free stem cell preservation in Cryo-Save. Can the umbilical cord stem cells be used for treatment of parents or siblings? When a patient receives cells donated by other individual, we are talking about allogeneic transplantation. In order for the treatment to be successful, they are often combined with special drugs, although even then the cells can be rejected. Therefore, always when possible, doctors prefer to use stem cells of the patient himself, i.e. the autologous transplantation. The probability that the preserved stem cells from the umbilical cord will be used in treatment of close relatives, such as siblings, is 1 : 4 (ideal donor-recipient match) and 1 : 2 (acceptable donor-recipient match). Additionally, umbilical cord stem cells are less likely to be rejected than the bone marrow cells.
What if the mother gives birth with a Caesarean section? Taking a stem cell sample in case of Caesarean section is completely the same as with the physiological childbirth. Regarding the simplicity of the procedure itself, the primary attention of the responsible doctor and the medical staff is always directed towards the mother and the baby. When twins or triplets are in question, there is a need for one container for collecting the sample for each baby. The collection procedure is repeated for each baby separately. Cryo-Save offers you a 50% price discount for the second and for the third child. Recommendations for Families As soon as the parents decide to preserve their children’s stem cells, they require answers to a number of questions – to whom they should address and how long before the childbirth, who is collecting the blood from the cord, what happens with the blood afterwards, how much money should they plan... We would advice future parents, before making decision to preserve stem cells from their newborns, to inform themselves well whether the bank which they would select is accredited by official
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Vidovi mati~ni kletki, koi treba da gi za~uvame i zo{to e toa potrebno? Papo~nata vrvca e bogat izvor na dva vida mati~ni kletki: krvotvorni (hematopoetski) i tkivotvorni (mezenhemalni). Krvotvornite mati~ni kletki se kletki od koi {to se sozdavaat elementite na krvta i imuniot sistem i nao|aat primena vo lekuvawe na okolu 80 seriozni zaboluvawa na krvta i bolesti povrzani so krvta. Tuka spa|aat nasledni anemii, maligni zaboluvawa na krvta (leukemii i limfomi), bolesti na imuniot i metabolniot sistem. Vtoriot vid na mati~ni kletki za razlika od prvite koi ve}e se upotrebuvaat vo standardnata medicina i ~ija humana aplikacija e definirana, se kletki so ogromen potencijal za upotreba za terapija za vo idnina. Tie imaat golema regenerativna mo} i denes mnogu klini~ki studii intenzivno rabotat na razvoj na terapii za pove}e zaboluvawa kako dijabet, Parkinsonova, Alchajmerova bolest, multipleks skleroza, detska paraliza itn. Postoi mo`nost da se za~uvaat samo kletkite od krvta kako rezerva za terapii koi ve}e se standardizirani ili da se za~uvaat kletki i od krvta i od tkivoto kako semejstvoto bi imalo na raspolagawe i od dvata tipa mati~ni kletki i toa ne samo za vozmo`nite tretmani denes, tuku i za toa {to se o~ekuva da se razvie vo idnina. Istra`uvawa niz svetot povrzani so mati~nite kletki Osven svetski priznatite dene{ni primeni na mati~nite kletki, kako {to se tretman na leukemija, karakteristi~ni formi na anemija, limfomi i drugi zaboluvawa, nau~nite istra`uvawa se razvivaat so golema brzina. Rasprostranet e optimizmot na nau~nata zaednica za raznolikosta na mo`nata upotreba na mati~nite kletki za tretman na golem broj bolesti, kako {to se: kardio-vaskularni bolesti, Dijabetes, maligni tumori, Parkinsonova bolest, Alchajmerova bolest, muskulni o{tetuvawa, cerebralni infarkti... Isto taka, istra`uvawata se naso~eni i kon razmno`uvawe na brojot na zemenite mati~ni kletki i nivno specijalizirawe vo laboratoriski uslovi se dodeka ne se postigne nivna ponatamo{na ekspanzija za terapevtska upotreba. Grupa na lu|e ili poedinci na koi im e prepora~livo da za~uvaat mati~ni kletki Odlukata za ~uvawe na mati~ni kletki od papo~nata vrvca na novorodeno ima posebno zna~ewe za lica koi pripa|aat na slednive grupi: semejna istorija na maligni bolesti, bolesti na krvta, bolesti koi se tretiraat so transplantacija na mati~ni kletki; parovi so me{ana nacionalnost, zaradi pomalite {ansi za nao|awe na kompatibilen daritel vo slu~aj na potreba; i bremenosti posle zabremenuvawe so ve{ta~ko oploduvawe ili in vitro oploduvawe so upotreba na tu|a sperma ili jajce kletka. Navedenite kategorii se tretiraat kako semejstva so visok rizik i zatoa preporakite za niv se mnogu porigorozni iako za~uvuvaweto na mati~ni kletki od papo~na vrvca kako postapka visoko se prepora~uva i za sekoe semejstvo koe o~ekuva prinova. So cel da im pomogne na semejstvata koi navistina imaat potreba, Cryo-Save vo Makedonija ve}e treta godina sproveduva kampawa za besplatna semejna donacija i pove}e od {esnaeset semejstva koi imaat ~len koj boleduva ili boleduval od bolest koja mo`e da se lekuva so mati~ni kletki, imaat dobieno besplatno za~uvuvawe vo Cryo-Save. Dali so kletkite od papo~nata vrvca }e mo`at da se lekuvaat roditelite ili bra}ata i sestrite na deteto? Koga pacientite }e dobijat kletki koi se donirani od drugo lice, zboruvame za alogena transplantacija. Za tretmanot da bide uspe{en tie ~esto se kombiniraat so specijalni lekarstva, iako, duri i toga{, kletkite mo`e da bidat otfrleni. Zatoa, sekoga{ koga e vozmo`no, lekarite pretpo~itaat upotreba na kletki od samiot pacient, odnosno, avtologna transplantacija. Verojatnosta za~uvanite mati~ni kletki od papo~na vrvca da se upotrebat za tretman na bliski rodnini, kako bra}a i sestri e 1 : 4 (idealna sovpadlivost) i 1 : 2 (prifatliva sovpadlivost). Dopolnitelno, postoi pomala mo`nost kletkite od papo~na vrvca da bidat otfrleni sporedbeno so kletkite od koskena sr`. [to dokolku majkata se porodi so carski rez? Zemaweto na primerok na mati~ni kletki vo slu~aj na pora|awe so carski rez se izveduva na potpolno ist na~in kako i kaj fiziolo{koto poroduvawe. So ogled na ednostavnosta na samata procedura, primarnoto vnimanie na odgovorniot lekar i na bolni~kiot personal e sekoga{ naso~eno kon majkata i bebeto. Dokolku se raboti za bliznaci ili pak za