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Canbex Therapeutics Announces Start of Phase I Trial Canbex Therapeutics Ltd. has announced the beginning of a Phase I study to determine the safety and effectiveness of its oral compound, VSN16R, for the treatment of spasticity in people living with MS. The VSN16R molecule relieves spasticity in mice without causing side effects such as flaccidity, sedation or mood alteration, which can occur with current approved spasticity treatments. With support from the National MS Society through its Fast Forward initiative, in November Canbex Therapeutics completed toxicity studies in rats, one of the final steps needed before bringing the molecule to human testing. This study was one of the National MS Society’s first commercial collaborations through Fast Forward and the first to advance a specific symptom treatment for MS. This trial, and further Phase II and Phase III studies, will help determine whether VSN16R has potential to develop into a safe and effective treatment for MS spasticity and to improve the quality of life for people living with MS.
National MS Society Partners With Accelerated Cure Project’s MS Discovery Forum The National MS Society has awarded the Accelerated Cure Project’s Multiple Sclerosis Discovery Forum a two-year, $150,000 grant to develop resources and content focusing on progressive MS. While the FDA has made substantial progress in approving therapies for relapsing forms of MS, none of these can stop progression or reverse the damage to restore function, which are critical for everyone living with MS, including those with progressive forms. The Multiple Sclerosis Discovery Forum was established in 2012 as a free, neutral venue where members of the MS research community can learn about cutting-edge findings, participate in discussions and access professional resources. The society’s partnership with the Discovery Forum is just one aspect of a multifaceted approach to increasing progress in this underexplored area of research that will enable the society to focus additional coverage and resources on progressive forms of MS. For more information on these research briefs, visit www.nationalMSsociety.org.
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Acorda Therapeutics Richard Chevrolet, Inc. Xerox Corporation ADDITIONAL SUPPORTERS
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