Agilent ZORBAX Silica
The Benefits of Strong Particles – Greater Efficiency and Durability During the silica manufacturing process, the agglutinated sol particles are sintered for increased strength. This improved mechanical stability allows ZORBAX columns to be packed at high pressures when needed – up to 14,000-15,000 psi. This results in a packed column with an exceptionally stable column bed that will not compress under normal or even high operating pressures – up to 18,000 psi (1200 bar). This packed bed stability increases column lifetime using ZORBAX 1.8, 3.5, 5 or 7 um particles. When ZORBAX Rapid Resolution HD or HT 1.8 μm and Rapid Resolution 3.5 μm silica particles are used as the underlying support, high speed, high efficiency chromatography is possible without compromising column lifetime.
The Benefits of Careful Pore Size and Particle Size Control – High Efficiency and Better Reproducibility with More Column Choices Accurate and closely monitored particle and pore size control for ZORBAX Rx-SIL produces reproducible retention behavior from column-to-column and lot-to-lot. The narrow, consistent particle size distribution of ZORBAX Rx-SIL particles maximizes efficiency and column bed stability. Column pressure is never unusually high due to "fines" – smaller particles at the low end of the particle size distribution. Accurate and precise control of particle size allows specific 1.8, 3.5, 5 and 7 μm particles to be produced. The small 3.5 μm and 1.8 μm particle sizes are the basis for the Rapid Resolution and Rapid Resolution HD and HT, high-speed analysis columns designed to maximize resolution in shorter column lengths – ideal for LC/MS or any application demanding shorter analysis times. The 5 μm particles are an industry standard and provide high resolution in a wide variety of column dimensions. This particle size also provides high efficiency in a short preparative configuration – the PrepHT column – because careful particle size control means consistent pressure expectations within normal operating limits. The 7 μm particle size provides the ideal balance between efficiency and operating pressure for longer preparative columns.
ZORBAX Rx-SIL – The Foundation for Many Bonded Phases With such strong performance characteristics, ZORBAX Rx-SIL particles have been developed into many effective bonded phases for solving key analytical problems. These include columns that can be used at extremes of pH, unmatched by any other silica-based columns. Because silica-based columns have different limitations at low and high pH, specific bonded-phase chemistries are required to provide longer column life over different pH ranges. As a result, Agilent ZORBAX RP-HPLC bonded phases are designed to give extended column lifetime and reproducibility in the pH ranges that provide optimum and long-lasting resolution, all starting with high performance ZORBAX Rx-SIL.
LC AND LC/MS COLUMNS
817