DiseaseOriented Research guiding equipment and chest protection techniques. The first single-center randomized trial on ELIOT was completed in December 2007. For this trial the Division recruited 1306 patients undergoing conservative surgery for breast cancer, and randomized then either to traditional external radiotherapy or ELIOT. Follow-up is still ongoing. A further example of multidisciplinary treatment is the co-operation carried out during the Nipple-sparing mastectomy which is a surgical technique developed in order to spare the nipple-areola complex in patients requiring mastectomy. During this operation the surgeons of the Senology Division work in close collaboration with the Plastic Surgery Division to achieve the best cosmetic outcome and, thanks to the intervention of the Radiotheraphy and Physics staff, ELIOT is used to irradiate the nipple-areola complex to ensure that it can be safely conserved. In patients undergoing conservative surgery in whom a subsequent asymmetry can be estimated, a bilateral reshaping can be performed to ensure the best possible cosmetic outcome. Our Division strictly cooperates with colleagues of the Medical Oncology department during the multidisciplinary meeting which is weekly held in which every patient operated for either invasive or intraductal neoplasia is discussed to define the postoperative adjuvant treatment along with Radioterapists, Pathologists, and physicians of the Cancer Prevention and Genetics Division. With these latter colleagues it is generally discussed the management of women at “high risk” and the participation of patients to “window of opportunity” trials.
for the International Breast Cancer Study Group Trial 23–01 investigators. Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial. Lancet Oncology 2013 Mar 8. pii: S14702045(13)70035 Veronesi U, Stafyla V, Petit JY, Veronesi P. Conservative mastectomy: extending the idea of breast conservation. Lancet Oncology 2012 Jul;13(7): e311-7 Gentilini O, Botteri E, Veronesi P, Sangalli C, Del Castillo A, Ballardini B, Galimberti V, Rietjens M, Colleoni M, Luini A, Veronesi U. Repeating conservative surgery after ipsilateral breast tumor reappearance: criteria for selecting the best candidates. Ann Surg Oncol 2012 Nov;19(12):3771-6 Gentilini O, Veronesi U. Abandoning sentinel lymph node biopsy in early breast cancer? A new trial in progress at the European Institute of Oncology of Milan (SOUND: Sentinel node vs Observation after axillary UltraSouND) The Breast 2012 Oct;21(5):678-81 Toesca A, Spitaleri G, De Pas T, Botteri E, Gentilini O, Bottiglieri L, Rotmentsz N, Sangalli C, Marrazzo E, Cassano E, Veronesi P, Rietjens M, Luini A. Sarcoma of the breast: outcome and reconstructive options. Clin Breast Cancer 2012 Dec;12(6):438-44
Publications Galimberti V, Cole BF, Zurrida S, Viale G, Luini A, Veronesi P, Baratella P, Chifu C, Sargenti M, Intra M, Gentilini O, Mastropasqua MG, Mazzarol G, Massarut S, Garbay JR, Zgajnar J, Galatius H, Recalcati A, Littlejohn D, Bamert M, Colleoni M, Price KN, Regan MM, Goldhirsch A, Coates AS, Gelber RD, Veronesi U.
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IEO — Scientific Report 2012 — Ongoing Research 2013
IEO — Scientific Report 2012 — Ongoing Research 2013
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