Inspired - Winter 2013 - University of Chicago Medicine
Inspired magazine is published three times a year by the University of Chicago Medicine. The publication is designed to keep referring physicians and research colleagues updated on all that is happening at the University of Chicago Medicine and the Biological Sciences Division, the Forefront of Medicine and Science.
Inspired WINTER 2013 A P H YS I C I A N P U B L I C AT I O N OPENING FEBRUARY 23 The Center for Care and Discovery The University of Chicago Medicine & Biological Sciences has been at the forefront of medical care, research and teaching for more than 90 years. Located in historic Hyde Park on the South Side of Chicago, the University of Chicago Medicine & Biological Sciences includes: Patient Care » Bernard A. Mitchell Hospital » Center for Care and Discovery » Comer Children’s Hospital » Duchossois Center for Advanced Medicine » Numerous outpatient locations throughout the Chicago area Teaching Programs » Pritzker School of Medicine » Master’s and doctoral degree programs » Postdoctoral programs Research » Medical and basic science units Among our many honors and acknowledgments: 12 Nobel laureates; ranked 10th of all U.S. medical schools; one of only 41 National Cancer Institute-designated Comprehensive Cancer Centers; ranked second in nation for National Institutes of Health grant support per researcher. University of Chicago Medicine & Biological Sciences Executive Leadership Kenneth S. Polonsky, MD, Dean of the University of Chicago Biological Sciences Division and the Pritzker School of Medicine, and executive vice president for Medical Affairs for the University of Chicago Sharon O’Keefe, president of the University of Chicago Medical Center Richard Baron, MD, dean for clinical practice, University of Chicago Medicine T. Conrad Gilliam, PhD, dean for research and graduate education, Biological Sciences Division Holly J. Humphrey, MD, dean for medical education, Pritzker School of Medicine INSPIRED IS PUBLISHED QUARTERLy By THE UNIVERSITy OF CHICAGO MEDICINE & BIOLOGICAL SCIENCES. Editors Anna Madrzyk and Ginny Lee-Herrmann Email us at: email@example.com Design TOKY Branding + Design Contributing writers Katie Scarlett Brandt, Tanya Cochran, Gretchen Rubin and Anita Slomski Contributing photographers David Christopher, Stephanie Dahl, Dan Dry, Brian Fritz, Grace Cheung Izquierdo, Jean Lachat, Bruce Powell and Thomas Rossiter ADDRESS The University of Chicago Medicine 5841 S. Maryland Ave., Chicago, IL 60637 The University of Chicago Medicine Comer Children’s Hospital 5721 S. Maryland Ave., Chicago, IL 60637 Telephone 1-773-702-1000 Appointments 1-888-824-0200 Follow the University of Chicago Medicine on Twitter at twitter.com/UChicagoMed or visit our Facebook page at facebook.com/ UChicagoMed. You can read more about our news and research at uchospitals.edu/news and at sciencelife.uchospitals.edu. This publication does not provide medical advice or treatment suggestions. If you have medical problems or concerns, contact a physician who will determine your treatment. Do not delay seeking medical advice because of something you read here. For urgent needs, call 911 right away. Read Inspired online at uchospitals.edu/inspired. AT T H E F O R E F R O N T O F M E D I C I N E ® The Center for Care and Discovery brings the best minds in research and medicine together to work in close collaboration, aided by the latest in technology. DeaR cOlleaGUes, Our Center for Care and Discovery is more than a new hospital; it’s an extraordinary step forward in clinical care. When it opens this month, the $700 million, state-ofthe-art facility will bring the best minds in research and medicine together to work in close collaboration, aided by the latest technology. More than a building, it will be a catalyst for our next wave of contributions to science and healing. As an architectural and technological tour de force, the Center for Care and Discovery will provide a home for complex specialty care with a focus on cancer, gastrointestinal disease, neurosciences, advanced surgery, advanced cardiovascular diagnostic and treatment services, and high-technology medical imaging. Just as important, however, is the center’s promise to transform the patient experience. Obviously, we are proud of our new hospital and its promises of innovative medical research and patient-centered care. We hope you enjoy reading about the Center for Care and Discovery and the potential it holds for the future of science and medicine. With the latest in diagnostic equipment and minimally invasive surgical tools, recoveries are quicker and discomfort minimized. To aid healing, the center’s 240 private, light-filled patient rooms, each with inspirational views of Chicago and beyond, are wired for the latest in nurse-patient communications and remote health monitoring, ensuring that needs are met quickly and efficiently. And features like ﬂat-screen televisions, wood accents and space for family members to stay overnight surround patients and their loved ones in comfort. KENNETH S. POLONSKY, MD Dean of the University of Chicago Biological Sciences Division and the Pritzker School of Medicine, and executive vice president for Medical Affairs for the University of Chicago INTRODUCING OUR NEw HOSPITAL THE CENTER FOR CARE AND DISCOVERy A hospital for the future The center for care and Discovery is dedicated to providing the most advanced health care to patients of today and tomorrow, with a focus on cancer, digestive diseases, neurosciences, advanced surgery and high-tech medical imaging. private patient rooms 240 21 A focus on exceptional patient care Our new hospital is designed for familycentered care and improved communication among all members of the patientâ€™s care team, transforming the patient experience. A setting for world-class research The center for care and Discovery is strategically located near the Gordon center for Integrative science and the Gwen and Jules Knapp center for Biomedical Discovery, two world-class research facilities where researchers are translating scientific discoveries into better care for patients. operating rooms with leading-edge technology; space for up to seven additional ORs An investment in the community The University of chicago Medicine chose to make this project an economic engine for the community by partnering with local, minority- and women-owned businesses. Intensive Care Unit beds 52 HE L I PA D CA N CE R CA R E GRE E N ROOF P R I VAT E I N PATIENT ROOMS The Center for Care and Discovery is located at 5700 S. Maryland Ave. on the University of Chicago campus. S KY LO B BY S UR G E RY DI AG N OST I C A ND F UT URE TE CH NOLOGY Ex PANSI ON SPACE I N T E RVE N T I O NAL MEDICINE P H ARMACY R E TA I L A N D DI N I N G PhysIcIan RefeRRal lIne 1-800-824-2282 | UCHICAGOKIDSHOSPITAL.ORG | UCHOSPITALS.EDU Âť 1 SOLVING PUZZLE ABOUT BIRD BRAINS Research News DEVILISH PLANT TARGETS CANCER a seemingly unique part of the human and mammalian brain is the neocortex, a layered structure on the outer surface of the organ where most higher order processing is thought to occur. But new research at the University of chicago has found cells similar to those of the mammalian neocortex in a vastly different anatomical structure (the dorsal ventricular ridge) in the brains of birds. The work, published in Proceedings of the National Academy of Sciences, confirms a 50-year-old hypothesis that a mysterious area in bird brains performs a similar function to the neocortex in mammals. senior author clifton Ragsdale, PhD, associate professor of neurobiology, says the study sheds new light on the evolution of the brain and opens up new animal models for studying the neocortex. AT THE FOREFRONT legend has it the cure for cancer is buried in the root of some obscure plant in the amazon rain forest. While that’s overstating what one medicine can do to fight the disease, University of chicago Medicine researchers found that an extract from the Pacific northwest shrub Oplopanax horridus, or devil’s club, can kill colorectal cancer cells without affecting normal cells. Wei Du, PhD, professor in the Ben May Department for cancer Research, and chun-su yuan, MD, PhD, director of the Tang center for herbal Medicine Research at the University of chicago, showed that the compound falcarindiol (faD) destroyed cancer cells by inducing a process called endoplasmic reticulum (eR stress), which interferes with the cell’s ability to rid itself of proteins that build up waste. In the paper published in Cell Death and Disease, Du said the results suggest faD “can potentially be used to develop better and safer therapies for colorectal cancers.” AT THE FOREFRONT FAMILY-CENTERED CARE Patient rooms in the Center for Care and Discovery are spacious, with comfortable furnishings for family visits and overnight stays. Amenities include Wi-Fi and flat-screen TVs with access to movies and games. NEw TARGET FOR CANCER TREATMENT EVEN FAT CELLS NEED SLEEP nUMBeR One #1 cancer program in Illinois in U.S. News & World Report’s 2012 rankings In a study that challenges the notion that the primary function of sleep is only to rest the brain, University of chicago Medicine researchers found that not getting enough shut-eye has a harmful impact on fat cells, reducing their ability to respond to insulin. sleep deprivation has long been associated with impaired brain function, causing decreased alertness and cognitive ability. The latest finding, published in the Annals of Internal Medicine, is the first description of a molecular mechanism directly connecting sleep loss to the disruption of energy regulation in humans, which can lead to weight gain, diabetes and other health problems. “Body fat serves a vital function in storing and releasing energy,” said author Matthew Brady, PhD, who studies metabolic signaling in his lab at the Kovler Diabetes center. “We found that fat cells need sleep to function properly.” The heR (human epidermal growth factor) family of receptors has been linked to the development of a variety of human cancers. heR1 inhibitors such as Iressa and heR2 inhibitors such as herceptin are commonly used for treatment of small cell lung carcinoma and breast cancer. a recent study, published in the online publication PLOS ONE, suggests that heR3 levels can predict reduced breast cancer survival. Using a sensitive method to analyze protein interactions, University of chicago Medicine researchers showed that heR3 could be up to 10 times more effective than heR2 in recruiting accessory factors that drive rapid progression, enhanced survival and distant spread of cancers, which are all hallmarks of malignancy. “When cancer grows resistant to such treatments as herceptin, we believe that heR3 has the potential to assume the new disease-promoting role,” said study author, Richard B. Jones, PhD, assistant professor in the Ben May Department for cancer Research. 2 » THE UNIVERSITY OF CHICAGO MEDICINE INSPIRED MAGAZINE | WINTER 2013 AN EXCEPTIONAL PLACE FOR HEALING [ T H E C E N T E R F O R C A R E A N D D I S C O V E R Y, S K Y L O B B Y ] As the heart of the hospital, the Sky Lobby consists of central reception, family waiting areas, a chapel and other public spaces — a place to be welcomed, to gather, to rest and to pray. RAFAEL VIÑOLY, ARCHITECT SKY LOBBY ART The Sky Lobby features floor-to-ceiling glass walls, filling the space with natural light and providing panoramic views of the campus, Lake Michigan, Washington Park and downtown Chicago. SOLACE Art can humanize the medical environment and play a role in the healing process. The Center for Care and Discovery’s Art Collector Committee selects inspiring and engaging artwork to bring respite, tranquility and confidence to the patient experience. MUSIC Tucked away on the seventh-floor Sky Lobby, the chapel provides patients and their families with a place for reflection, prayer and meditation. Blue tiles enclose a peaceful space in which curved wooden walls are crowned by a ring of light shining through a circle of windows. Music soothes and lifts the human spirit. A baby grand piano will enhance the sense of warmth and community in the open lobby. PhysIcIan RefeRRal lIne 1-800-824-2282 | UCHICAGOKIDSHOSPITAL.ORG | UCHOSPITALS.EDU » 3 READy FOR THE GREATEST CHALLENGES I N M E D I C I N E , S C I E N C E & P AT I E N T C A R E The Center for Care and Discovery provides a home for complex specialty care with a focus on cancer, digestive diseases, neurosciences, advanced surgery, advanced cardiovascular diagnostic and treatment services, and high-technology medical imaging. 4 Âť THE UNIVERSITY OF CHICAGO MEDICINE INSPIRED MAGAZINE | WINTER 2013 CARDIOVASCULAR Innovative Options for Patients Designed for innovation and collaboration, the center for care and Discovery advances the University of chicago Medicine’s programs in cardiac catheterization, minimally invasive and robot-assisted surgery, cardiovascular surgery and heart transplantation. Interventional suites and operating rooms in the hospital feature sophisticated diagnostics and leadingedge medical technologies for cardiac care, including state-of-the-art imaging. “The imaging capabilities in the new hospital will allow us to perform highly intricate procedures in the safest possible way,” said Ross Milner, MD, vascular surgeon and co-director of the aortic diseases program. Many heart patients who come to the University of chicago Medicine have complex disease. some have been turned away by other institutions. Our cardiologists, interventional cardiologists, cardiac surgeons and vascular surgeons work together to ensure patients get the most appropriate care — whether medical, interventional or surgical. “We are committed to delivering superb care to medically complex patients in substantial collaboration with our surgical colleagues,” said interventional cardiologist sandeep nathan, MD, Ms. That care includes options for robotassisted and minimally invasive approaches to cardiac and vascular surgery, groundbreaking device therapies and clinical trials. University of chicago Medicine cardiac surgeons are known for their expertise in ventricular assist device implants, heart valve repair and replacement, cardiac reconstruction and heart and multi-organ transplants. Our vascular surgeons are pioneers in the treatment of complex diseases of the arteries, including hybrid procedures for abdominal aortic aneurysms, carotid artery disease and peripheral arterial disease. | l e f T | Jeffrey B. Matthews, MD, is surgeon-in-chief at the University of Chicago Medicine. Read more about Matthews and the Center for Care and Discovery on page 11. D I S COV E Ry 1900s A University of Chicago cardiac surgeon performs the first heart transplant on a dog. I N N O VAT I O N PATIENT STORY “all the top experts are here. There really is no place I’d rather be.” SCOTT BELASCO 1999 University of Chicago Medicine physicians perform the first successful heartliver-kidney transplant. ONE ROOM, MANy PROCEDURES Hybrid operating rooms unite the surgical suite and the cardiac catheterization lab, enabling cardiac surgeons and interventional cardiologists to perform multiple diagnostic, interventional and surgical procedures in one setting. The fully integrated hybrid ORs are equipped with the newest technology and tools, including a video X-ray system, intravascular ultrasound and videoconferencing. LIVE FROM THE O P E R AT I N G R O O M Integrated videoconferencing equipment enables surgeons to communicate directly with specialists throughout the medical center and in other facilities, conduct “at-the-point” teaching for medical trainees, and consult with patients’ family members in the hospital and anywhere in the world. In October, scott Belasco, 56, of long Grove, Ill., became the first person in the U.s. to be implanted post-fDa approval with a new type of defibrillator with leads just under the skin rather than connected to the heart. his physician, Martin c. Burke, DO, also implanted the first such device in the U.s. clinical trial, which began in 2010. JAMES K. LIAO, MD, APPOINTED CARDIOLOGY CHIEF James K. liao, MD, an internationally recognized authority on blood vessel biology and vascular disease, has been named section chief of cardiology at the University of chicago Medicine. liao came to the University of chicago from harvard Medical school, where he was director of vascular medicine research at Brigham and Women’s lIaO hospital. liao has made significant contributions to the medical literature, publishing more than 125 articles in scientific journals including Science, Nature and Nature Medicine. “cardiology at the University of chicago Medicine has many traditional strengths, including leading programs in heart failure and transplantation, cardiac imaging, electrophysiology, hypertension and disease prevention,” liao said. “I hope to build on those achievements and to help the section enhance its reputation as one of the top cardiovascular programs in the country.” PhysIcIan RefeRRal lIne 1-800-824-2282 | UCHICAGOKIDSHOSPITAL.ORG | UCHOSPITALS.EDU » 5 Collaborative Neurological Care The design of the Center for Care and Discovery supports the advanced technology and collaboration essential for leading-edge neurological care. Neuroscience facilities in the Center for Care and Discovery include two neuroangiography suites, where minimally invasive procedures are performed for the diagnosis and treatment of brain, head and neck, spine and spinal cord conditions. These neurointerventional techniques can be applied to brain aneurysms and arteriovenous malformations, to emergent intervention on acute ischemic stroke, and in caring for pediatric patients from the adjacent University of Chicago Medicine Comer Children’s Hospital when they require complex endovascular neurointervention. “Everything we need to deliver leading-edge neurointerventional care — an expert team of neurosurgeons and neurologists, advanced imaging, patient-oriented nursing and support services — will be close by and tightly organized,” said Seon Kyu Lee, MD, PhD, director of interventional neuroradiology. The surgical suites feature the latest in OR technology, including intraoperative imaging modalities. These tools give neurosurgeons better localization of tumors and real-time feedback, enabling them to take on the most difﬁcult cases. The Neuro-Intensive Care Unit is equipped with the full range of telemetry and the latest technology, including continuous brain wave monitoring and portable CT imaging. The adjacent neurosciences inpatient unit includes high-level neuromonitoring capabilities, such as highdensity EEG capability as well as several modalities of neurophysiological recordings, in every patient room. “Because the Neuro-ICU and dedicated neurosciences inpatient rooms are adjacent to each other in the new hospital, we can seamlessly move patients between the two units,” said David M. Frim, MD, PhD, chief of neurosurgery. “Moving patients out of the ICU sooner and helping them convalesce faster will greatly enhance the patient experience.” NEUROSCIENCES A D VA N C E D I M AG I N G Neurointerventional suites in the Center for Care and Discovery are equipped with MRI, CT scan, CT angiography, ultrasound and X-ray modalities. Surgical suites feature the latest in OR technology, including intraoperative imaging. PATIENT STORY EXPERT CARE The Neuro-Intensive Care Unit is staffed full time by neurological and neuro-critical care specialists. “It is always important to ﬁnd the best doctor to take care of you. For me, that meant coming to Chicago.” SHERRY KEDRA CLEAN AIR ZONES Every surgical suite features a laminar airﬂow system designed to create a clean zone around the patient. A curtain of air around the operating table creates an invisible barrier to microorganisms in the air. Ohio resident Sherry Kedra sought out experts at the University of Chicago Medicine after experiencing a bleed into her brain. Neurosurgeon Issam A. Awad, MD, successfully removed the damaging lesion in a four-hour procedure and neuro-critical care experts managed her post-surgical care. Using special MRI studies being developed here, our physicians will continue to monitor the 40-year-old nurse for years to come. 6 » THE UNIVERSITY OF CHICAGO MEDICINE INSPIRED MAGAZINE | WINTER 2013 FASTER COMMUNICATION Patient calls for assistance go directly to the nurse’s wireless phone, instead of ringing at a nurses’ station. The new call system also enables nurses to receive direct phone calls from other care providers and the patient’s family. ADVANCED SURGERY sandra culbertson, MD, a specialist in urogynecology, says that robotassisted surgery offers her patients quality-of-life improvements. Robotic-Assisted Precision The spacious robotic operating rooms in the center for care and Discovery feature two state-of-the-art da Vinci surgical systems. This sophisticated surgical technology provides high-definition, three-dimensional views inside the body. The device enables surgeons to perform complex operations with greater precision, improved dexterity and enhanced visualization. a dual console facilitates teaching and collaborative surgery. Urologist arieh l. shalhav, MD, chief of urology and director of minimally invasive urology, first used the system to operate on a patient at the University of chicago Medicine in 2002. To date, his team has performed approximately 3,400 robotic prostatectomies. “Our surgeons are highly experienced and each one has developed a super-specialization,” shalhav said. “now we are pushing the envelope and tackling more complex cases.” DA V I N C I 3,400 robotic prostatectomies performed at the University of Chicago Medicine. I N N O VAT I O N Our surgeons are recognized experts on minimally invasive surgery for children and adults. Mohan S. Gundeti, MD, director of pediatric urology, recently performed an innovative robot-assisted procedure that was broadcast live to surgeons from around the country. “We get them home in 24 hours and back to normal activities sooner.” SANDRA CULBERTSON, MD Robotic surgical instruments continue to get smaller and more flexible, allowing other specialties to apply the technology. for example, thoracic surgeons here recently began using the da Vinci system. “Patients knew about the advantages of the robotic technique and were asking for it,” said cardiothoracic surgeon Wickii T. Vigneswaran, MD, associate chief of cardiac and thoracic surgery. “We are performing thoracic procedures with more precision than ever before.” PhysIcIan RefeRRal lIne 1-800-824-2282 | UCHICAGOKIDSHOSPITAL.ORG | UCHOSPITALS.EDU » 7 ROOMS wITH A VIEw Patient rooms are located on the perimeter of the building for greater privacy. Large windows provide stunning views of the campus, lakefront and Chicago skyline. Highly Complex, Minimally Invasive The state-of-the art endoscopy suites in the new center for care and Discovery enable the University of chicago Medicine’s interventional endoscopy experts to easily integrate emerging technology. “With surgical, imaging and endoscopy equipment now in one room, we perform multiple procedures on a patient in one session, which reduces repeat visits and shortens hospital stays,” said Irving Waxman, MD, director of the center for endoscopic Research and Therapeutics. “Working with surgical and interventional radiology colleagues, we also can do complex minimally invasive procedures.” Most medical centers, for example, treat complications of pancreatitis surgically, said andres Gelrud, MD, director of interventional endoscopy, who leads a new program for patients with pancreatic diseases. “here we remove necrotic pancreatic tissue through the mouth using a minimally invasive, endoscopic approach.” advanced interventional procedures include endoscopic ultrasound, endoscopic mucosal resection, peroral endoscopic myotomy and endoscopic retrograde cholangiopancreatography. The highly experienced team performs more than 2,000 interventional endoscopy procedures annually. “This contributes to our excellent patient outcomes and low rate of complications,” said Uzma siddiqui, MD, director of endoscopic ultrasound. Team members also have published their results on the use of probe-based confocal laser endomicroscopy, which provides 1,000 times magnification that allows a physician to see a real-time “virtual” biopsy on an endoscopy screen during a procedure. DIGESTIVE DISEASES D E D I C AT E D S P A C E 12 rooms dedicated for gastrointestinal and pulmonary procedures. FIRST PATIENT STORY 1934 Our physicians were the first in the U.S. to use the gastroscope. EXPERIENCE “The University of chicago Medicine gave me my life back.” JEFFERY SHAw 2,000 specialized ultrasound and interventional endoscopy procedures annually. wITHIN REACH Jeffery shaw of Phoenix, ariz., traveled to the University of chicago Medicine for treatment of achalasia, a rare disorder that prevents the esophageal sphincter muscle from relaxing and allowing food to pass into the stomach. By this time, he had lost 55 pounds as swallowing foods and liquids became progressively more difficult. Marco G. Patti, MD, director of the center for esophageal Diseases, removed a portion of shaw’s esophagus and reconstructed his GI tract. The 36-year-old IT company owner — and soon-to-be first-time father — is rediscovering the joy of eating. Imagine a bedside table with convenient shelves that put everything a patient needs for a comfortable hospital stay within easy reach. 8 » THE UNIVERSITY OF CHICAGO MEDICINE INSPIRED MAGAZINE | WINTER 2013 CANCER Customized and Comprehensive Care for physician-scientist Ravi salgia, MD, PhD, and his colleagues, it’s a short walk across the street from their research laboratories in the Knapp center for Biological Discovery to the new center for care and Discovery — the ideal setting for clinical testing of promising therapies. “The new hospital will speed the translation from laboratory to treatment and enhance the quality of life and survival for patients with cancer,” said salgia, director of thoracic oncology and vice chairman of translational research at the University of chicago Medicine. The University of chicago Medicine comprehensive cancer center is one of just 41 centers in the U.s. awarded the “comprehensive” designation from the national cancer Institute. Our clinicians are committed to creating customized, comprehensive care for all patients confronting a cancer diagnosis, including novel combinations of surgery, chemotherapy and radiation; new approaches to stem cell transplant; and the pioneering use of genetics to further personalize treatment. The top floor of the new hospital is devoted to cancer care, with 36 oncology rooms and a 28-bed Bone Marrow Transplant Unit. “each of the private rooms has telemetrymonitoring capabilities and an air filtering system for infection control,” said andrew artz, MD, a hematologist-oncologist. Patient rooms in the center for care and Discovery are spacious to accommodate family members for extended stays. amenities include foldout sofas, as well as family shower facilities on the floor. The unit includes two exercise rooms to help patients stay active and regain strength during hospitalization and treatment. “The unit is designed to be a place where patients can heal and recover with the support of family, friends and an outstanding nursing staff dedicated to each person’s needs,” said Richard l. schilsky, MD, professor emeritus at the University of chicago, who joins the american society of clinical Oncology this month as chief medical officer. THEN MICHAEL R. BISHOP, MD, NAMED BONE MARROw TRANSPLANT DIRECTOR 1972 Janet Rowley, MD, identifies the first recurring chromosomal abnormality associated with cancer, paving the way for targeted treatments. NOW 2010 The Center for Personalized Therapeutics opens, advancing efforts to tailor treatment plans to a patient’s genetic makeup. Michael R. Bishop, MD, an expert in the treatment of lymphoma and leukemia and in stem cell transplantation, has been appointed BIshOP bone marrow transplant director at the University of chicago Medicine. Bishop came to the University of chicago from the Medical college of Wisconsin, where he was the head of the adult hematologic malignancies section. Prior to his time there, he was a senior investigator and served as the clinical head of stem cell transplantation for the national cancer Institute at the national Institutes of health. In his new role, Bishop is interested in creating a comprehensive stem cell transplant program that includes a focus on the elderly population. In addition, his clinical and translational research will focus on the prevention and treatment of relapse after stem cell transplantation, the most common cause of therapy failure following the procedure. A TRANQUIL SETTING Adjustable lighting, room-darkening shades and soft colors create a soothing environment. PhysIcIan RefeRRal lIne 1-800-824-2282 | UCHICAGOKIDSHOSPITAL.ORG | UCHOSPITALS.EDU » 9 CME & EDUCATIONAL OPPORTUNITIES 18th Annual University of Chicago Radiology Review 2013 MARCH 4 – 8 For caregivers, the new building fosters cross-fertilization and real-time collaboration. DAVID H. SONG, MD, MBA Hyatt Chicago Magnificent Mile 633 N. Saint Clair St., Chicago Advanced Treatment Options in Heart Failure MARCH 9, 6 – 9 PM Fairmont San Francisco 950 Mason St., San Francisco, Calif. 10th Annual Current Concepts in Primary Care Sports Medicine MARCH 14 – 16 A S URGE O N’S P ERS P ECTI VE David h. song, MD, MBa, is vice chairman of the Department of surgery and chief of plastic and reconstructive surgery at the University of chicago Medicine. he specializes in reconstructive microsurgery for breast cancer, working in close collaboration with nora Jaskowiak, MD, director of surgery at the University of chicago Medicine Breast center. Q: HOw wILL THE CENTER FOR CARE AND DISCOVERY ADVANCE SURGERY? A: Q: wHY IS COLLABORATION SO IMPORTANT FOR BREAST CANCER RECONSTRUCTION? A: Millennium Knickerbocker Hotel 163 E. Walton Place, Chicago Live from University of Chicago! Endoscopic Advances for Clinical Practice APRIL 12 – 13, 2013 University of Chicago Medicine Center for Care and Discovery 5700 S. Maryland Ave., Chicago Specialty Review in Urology APRIL 19 – 24, 2013 Chicago Marriott Naperville 1801 N. Naperville Blvd., Naperville, Ill. 10th International Chicago Lymphoma Symposium APRIL 26 – 27 W Hotel Chicago City Center 172 W. Adams St., Chicago all the technology out there has been crystallized to enhance patient care in the center for care and Discovery. for caregivers, the building fosters and promotes cross-fertilization and real-time collaboration. We’ll have the technology to allow other members of the medical team, such as pathologists, to watch the surgery live. It’s all about providing each individual patient with the latest technique, teaching this to our residents and disseminating knowledge to our colleagues. The volume of cases we do here is unparalleled in the Midwest — almost 200 a year. The surgical oncologist wants to make sure the cancer is absolutely gone, but she knows what she has to do for me to have something to work with. at many places, patients see one doctor for the cancer resection, who then says, “now I’m done, and you’re off to another doctor.” here, patients go through the process without having to start over with consultations, because our team works together on each case. That’s the main benefit of having a reconstructive surgeon know about cancer and a cancer surgeon know about reconstruction. Q: wHAT TECHNIQUE DO YOU USE FOR BREAST RECONSTRUCTION AFTER CANCER? A: Register for CME events at cme.uchicago.edu. AT THE FOREFRONT Q: wHAT SETS PLASTIC AND RECONSTRUCTIVE SURGERY AT THE UNIVERSITY OF CHICAGO MEDICINE APART? A: HIGH TECH, HIGH TOUCH Every patient room is equipped for advanced monitoring. A computer at each bedside will allow nurses to document information immediately. We “get” complex. We’re leaders in reconstructive microsurgery — sewing tiny blood vessels under a microscope — in the Midwest. We’re internationally known for complex reconstructive surgery — cleft lip or palate, burns, a breast removed after cancer. The aesthetics of the result really are a priority. We specialize in the DIeP (deep inferior epigastric perforator) flap. Patients from the corners of the earth find us for this. I use abdominal tissue to reconstruct the breast, so essentially the patient also gets a tummy tuck. This technique spares the muscle with minimal pain. The national success rate is 94 percent to 95 percent. Ours is more than 99 percent — one of the highest in the world. 10 » THE UNIVERSITY OF CHICAGO MEDICINE INSPIRED MAGAZINE | WINTER 2013 Ask the Expert Jeffrey B. Matthews, MD, is surgeon-in-chief at the University of Chicago Medicine and chair of the Department of Surgery. He is a leading authority on the surgical treatment of diseases of the pancreas, bile ducts and liver. Q: HOw IS THE CENTER FOR CARE AND DISCOVERY A HOSPITAL FOR THE FUTURE? Physician Relations Program Please contact us by phone or email with any request. 1-773-234-2036 DIRECTOR Bucksbaum Institute for Clinical Excellence The Bucksbaum Institute for clinical excellence was created to improve patient care, to strengthen the doctor-patient relationship and to enhance communication and decision making between patients and physicians. The Bucksbaum Institute supports training and career development at three levels: medical students, junior faculty and senior faculty. senior faculty serve as master clinician role models for the students and junior faculty. Carol Marshall 1-773-702-9205 carol.marshall@ uchospitals.edu The design of the hospital creates a hightechnology environment for advanced M aT T h e W s care and new therapies, while at the same time meeting modern expectations of patients and families for warm, friendly and easily accessible accommodations and amenities. A: Q: CAN YOU DESCRIBE SOME OF THESE NEwER TREATMENTS? A: future increasingly will require such collaboration among surgery, medicine, radiology, pathology and other specialties. Q: wILL THE NEw FACILITY ADVANCE MEDICAL RESEARCH? A: ASSISTANT DIRECTOR Carrie Sota 1-773-892-2120 carrie.sota@ uchospitals.edu The immediate adjacency of this state-of-the-art clinical platform to the two newest and most advanced research facilities (the Gordon center for Integrative science and the Knapp center for Biomedical Discovery) will drive translational advances, by literally enhancing communication between the bench and the bedside. Q: wILL IT IMPACT MEDICAL EDUCATION? ASSOCIATES Anthony Turner South and Southwest suburbs 1-773-729-0822 anthony.turner@ uchospitals.edu Demetria Avant Western suburbs 1-773-717-0458 demetria.avant@ uchospitals.edu Dionne Meekins-Michaud All regions, pediatrics 1-773-717-0457 dionne.michaud@ uchospitals.edu Amber Naik North and Northwest suburbs 1-773-230-5236 amber.naik@ uchospitals.edu Michael DeLaRosa Northwest Indiana 1-773-230-8496 michael.delarosa@ uchospitals.edu MacLean Center for Clinical Medical Ethics The Maclean center for clinical Medical ethics examines ethical issues related to clinical medicine with the goal of improving the process and outcome of patient care. The first such program in the country, the center has gained national and international attention for its groundbreaking research and training in medical ethics. During the past 25 years, the Maclean center has trained more than 300 ethics fellows, many of whom are now leaders in the field. AT THE FOREFRONT Personalized cancer treatment regimens based on genomic data and molecular fingerprinting, robotic surgery and other forms of advanced minimally invasive interventions, hybrid heart procedures that combine innovative endovascular and off-pump techniques, imageguided surgery and other types of innovative emerging technology. A: Q: HOw wILL THE NEw HOSPITAL FOSTER COLLABORATION AND INTERACTIONS AMONG STAFF? A: The new hospital will support the full spectrum of the educational activities of the University of chicago, including its premier residency training programs and fellowships as well as the Pritzker school of Medicine. Wireless systems, video integration and immersive simulation tools will enhance the classroom experience and introduce new approaches to distance learning. | a B O V e | Jeffrey B. Matthews, MD, The new space is truly transformational in that it was specifically designed to increase interactions across different disciplines. advanced care for such complex conditions as cancer and cardiovascular disease in the is president of the Society for Surgery of the Alimentary Tract. He is one of a handful of surgeons in the nation with expertise in islet autotransplantation. 87 NOBEL PRIZE WINNERS associated with the University of Chicago, including 12 Nobel laureates who won for discoveries related to physiology or medicine PhysIcIan RefeRRal lIne 1-800-824-2282 | UCHICAGOKIDSHOSPITAL.ORG | UCHOSPITALS.EDU Âť 11 This will do wonders for our patients. TIwANA RIVERS, RN, BSN PATIENT CARE AT THE CENTER FOR CARE AND DISCOVERy Debra Albert, RN, MSN, MBA, NEA-BC, is a veteran administrator, nationally renowned for her leadership in improving the patient experience. She is chief nursing officer and vice president of patient care services at the University of Chicago Medicine. Q: IN wHAT wAYS wILL THE CENTER FOR CARE AND DISCOVERY CHANGE THE PATIENT ExPERIENCE? A: advanced technologies will increase our communication with patients, allowing us to tailor our responses to their specific needs. The GetWellnetwork, an interactive platform, will give patients direct access to educational health materials and entertainment. It also gives patients the ability to rate their pain, which could trigger intervention by the nurse. nurses will carry wireless phones, which will allow physicians and patients to talk to the nurses much faster. It’s all about empowering the patient and collaborating with physicians and other health care team members. Q: wHAT ARE YOUR GOALS AS CHIEF NURSING OFFICER? A: To provide all patients an experience above and beyond their expectations. Tiwana Rivers, Rn, Bsn, finds her work as a bone marrow transplant nurse extremely rewarding. “We care for patients, but we also advise them and advocate for them,” she said. “and we see patients given another chance to live their lives, be with family and reach their goals.” Rivers is excited about working on the new bone marrow transplant unit in the University of chicago Medicine center for care and Discovery. Here’s what she is looking forward to: THE ROOMS “Our patients are hospitalized for four to six weeks. Offering them a spacious and beautiful room that accommodates their family and their belongings is stellar.” “This will do wonders for our patients. It’s very difficult for them to be inside for weeks at a time. The wall of windows will bring the outside in.” “having telemetry in individual rooms helps nurses to be more efficient and to take better care of our patients.” THE VIEw TECHNOLOGY Q: wHO ARE TODAY’S NURSES AT THE UNIVERSITY OF CHICAGO MEDICINE? A: We have highly trained and educated nurses at the bedside, providing an advanced level of direct care. not only are they experts in their field, but they are models of benevolence in their daily acts of kindness and compassion. Q: HOw IS THE FACE OF NURSING CHANGING? A: We have multiple generations and second-career nurses coming into the field, each bringing entirely different perspectives based on their life experiences to their practice. The more diverse the profession, the more we mirror the patients we serve and the more capable we are of providing compassionate care to our patients. FAMILY AMENITIES “There’s no better way to support our patients than to make their families more comfortable when they stay here. It’s phenomenal.” AT THE FOREFRONT clinical advanced practice nurses at the University of chicago Medicine 150 12 » THE UNIVERSITY OF CHICAGO MEDICINE INSPIRED MAGAZINE | WINTER 2013 FA M I LY S U P P O RT S ALS RESEARCH A FATHER’S LEGACy even after his death, Doug MacInnes was the epitome of selflessness. The stay-at-home dad and triathlete, who succumbed to amyotrophic lateral sclerosis (als) just two years after his diagnosis, ensured that his wife of 29 years would still receive her 30th anniversary presents from him. “he got me this necklace with ‘30th’ on it and a pair of earrings. he placed them in a drawer and had our daughter emily wrap them with a promise to deliver them on my anniversary,” said sue MacInnes. “after he died, the next week on our anniversary I got my presents. That’s the type of person he was.” Doug was among the nearly 5,600 people in the U.s. diagnosed annually with als, a neurodegenerative disorder also known as lou Gehrig’s disease. shortly after her father’s diagnosis, Molly MacInnes, the youngest of Doug and sue’s three children, established steps for Doug, a nonprofit dedicated to raising money for als patients and their families. cOnTInUeD » als research is on fire, and we have some extraordinary new findings, especially related to genes. RAYMOND P. ROOS, MD Through a variety of fundraising events, the Trout Valley, Ill., family has raised more than $45,000. The family donated most of the funds to Doug’s physician, neurologist Raymond P. Roos, MD, director of the amyotrophic lateral sclerosis (als)/ Motor neuron Disease clinic at the University of chicago Medicine. “Despite all that we have learned about als over the last 20 years, we only have one drug that makes a difference and is fDa-approved,” he said. “That drug helps to extend life by three months, but does not improve quality of life. There is a desperate need for a more effective treatment.” Thanks to the MacInnes family and their contribution to his research, Roos, however, is optimistic about the future. “als research is on fire, and we have some extraordinary new findings, especially related to genes that cause als,” Roos said. “next year, there will be some very exciting new understandings, as well as a host of experimental models that will lead to the development of new drugs.” We want people to channel their energy into doing something good for als. MOLLY MACINNES For more information or to support ALS research at the University of Chicago Medicine, please contact Abbe Temkin at firstname.lastname@example.org. | l e f T | Sue MacInnes, second from left, with daughters Molly, left, and Emily Somers, son Chris and his girlfriend, Adrienne McCauley. | R I G h T | Doug MacInnes NONPROFIT ORGANIzATION U.S. POSTAGE PAID CAROL STREAM, IL PERMIT NO. 2003 The University of Chicago Medicine 5841 S. Maryland Ave. Chicago, IL 60637 If you receive an extra copy of this publication, please share it with a neighbor or friend. If you prefer to be removed from our mailing list, please call 1-855-622-6116. OPENING FEBRUARy 23 We have taken great care to design spaces within the unique architecture of the Center for Care and Discovery that enable us to provide the most technologically advanced care while maintaining a warm and friendly environment. A robust network of connectivity has been embedded into every aspect of patient care to maintain seamless communication between the patient, family members, the physician in charge, the referring doctor, and the entire care team. Connect with us for a superior patient experience and enhanced physicianto-physician communication at the University of Chicago Medicine. JOHN C. ALVERDY, MD Executive vice chair, Department of Surgery; director of minimally invasive surgery